SRO3_ARATH
ID SRO3_ARATH Reviewed; 305 AA.
AC O64592; F4I5F9; Q9CAM0;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 2.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=Probable inactive poly [ADP-ribose] polymerase SRO3;
DE AltName: Full=Protein SIMILAR TO RCD ONE 3;
GN Name=SRO3; Synonyms=CEO4; OrderedLocusNames=At1g70440;
GN ORFNames=F17O7.2, F24J13.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP INTERACTION WITH STO.
RX PubMed=11018516; DOI=10.1016/s0014-5793(00)02016-0;
RA Belles-Boix E., Babiychuk E., Van Montagu M., Inze D., Kushnir S.;
RT "CEO1, a new protein from Arabidopsis thaliana, protects yeast against
RT oxidative damage.";
RL FEBS Lett. 482:19-24(2000).
RN [4]
RP INDUCTION.
RX PubMed=20226034; DOI=10.1186/1471-2164-11-170;
RA Jaspers P., Overmyer K., Wrzaczek M., Vainonen J.P., Blomster T.,
RA Salojaervi J., Reddy R.A., Kangasjaervi J.;
RT "The RST and PARP-like domain containing SRO protein family: analysis of
RT protein structure, function and conservation in land plants.";
RL BMC Genomics 11:170-170(2010).
CC -!- FUNCTION: Probable inactive ADP-ribosyltransferase that may be involved
CC in stress and developmental responses. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with STO. {ECO:0000269|PubMed:11018516}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- INDUCTION: By salt stress. {ECO:0000269|PubMed:20226034}.
CC -!- CAUTION: Lacks the conserved catalytic triad His-Tyr-Glu of the active
CC site. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC18815.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC003671; AAC18815.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC010796; AAG52467.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35062.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59109.1; -; Genomic_DNA.
DR PIR; T01478; T01478.
DR RefSeq; NP_001321500.1; NM_001334450.1.
DR RefSeq; NP_177201.1; NM_105712.3.
DR AlphaFoldDB; O64592; -.
DR SMR; O64592; -.
DR BioGRID; 28600; 1.
DR STRING; 3702.AT1G70440.1; -.
DR PaxDb; O64592; -.
DR PRIDE; O64592; -.
DR ProteomicsDB; 226733; -.
DR EnsemblPlants; AT1G70440.1; AT1G70440.1; AT1G70440.
DR EnsemblPlants; AT1G70440.2; AT1G70440.2; AT1G70440.
DR GeneID; 843380; -.
DR Gramene; AT1G70440.1; AT1G70440.1; AT1G70440.
DR Gramene; AT1G70440.2; AT1G70440.2; AT1G70440.
DR KEGG; ath:AT1G70440; -.
DR Araport; AT1G70440; -.
DR TAIR; locus:2016159; AT1G70440.
DR eggNOG; ENOG502QWND; Eukaryota.
DR HOGENOM; CLU_062533_0_0_1; -.
DR InParanoid; O64592; -.
DR OMA; LYPANIH; -.
DR OrthoDB; 948541at2759; -.
DR PRO; PR:O64592; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O64592; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
DR InterPro; IPR012317; Poly(ADP-ribose)pol_cat_dom.
DR InterPro; IPR044964; RCD1/SRO1-5.
DR InterPro; IPR022003; RST.
DR PANTHER; PTHR32263; PTHR32263; 1.
DR Pfam; PF12174; RST; 1.
DR PROSITE; PS51059; PARP_CATALYTIC; 1.
DR PROSITE; PS51879; RST; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Nucleus; Reference proteome; Stress response.
FT CHAIN 1..305
FT /note="Probable inactive poly [ADP-ribose] polymerase SRO3"
FT /id="PRO_0000410421"
FT DOMAIN 23..249
FT /note="PARP catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00397"
FT DOMAIN 238..305
FT /note="RST"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01227"
SQ SEQUENCE 305 AA; 34501 MW; 430FDE72F931C787 CRC64;
MAAQVEIEDQ ESVTNLDNGE IINPISDNAP NFSGDATILL REATFEHNLI KNCFLSGMGS
FATETTIVTV RKILTQRLIT TKAKFAVFKL FTEAMKRKNN GYANIRYGWY SGSKEEIDRV
ITYGFSNREI KKVENDVGSH GVGIHLVHHR YSLAAALVGE GDEEGIKNIL LCRVILGKPE
QIVTGSKQSY PSSNQFDSGV DNLENPRKYV IWSCNMNSYI LPTYIVSFKS HLLRGLIGRA
RSPCVSFSVL MSILSKSLDA ARMNLILTSY DDFRKRKLRR EQLVRKIREV VGDNLLFKIL
KNQRR
