SRP09_ARATH
ID SRP09_ARATH Reviewed; 103 AA.
AC Q9SMU7;
DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 133.
DE RecName: Full=Signal recognition particle 9 kDa protein;
DE Short=SRP9;
GN Name=SRP9; OrderedLocusNames=At3g49100; ORFNames=T2J13.60;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC ribonucleoprotein complex that mediates the cotranslational targeting
CC of secretory and membrane proteins to the endoplasmic reticulum (ER)
CC (By similarity). SRP9 together with SRP14 and the Alu portion of the
CC SRP RNA, constitutes the elongation arrest domain of SRP (By
CC similarity). The complex of SRP9 and SRP14 is required for SRP RNA
CC binding (By similarity). {ECO:0000250|UniProtKB:P21262}.
CC -!- SUBUNIT: Heterodimer with SRP14; binds RNA as heterodimer (By
CC similarity). Component of a signal recognition particle complex that
CC consists of a 7SL RNA molecule and six protein subunits: srp72, srp68,
CC srp54, srp19, srp14 and srp9 (By similarity).
CC {ECO:0000250|UniProtKB:P21262, ECO:0000250|UniProtKB:P49458}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SRP9 family. {ECO:0000305}.
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DR EMBL; AL132967; CAB62000.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78498.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65982.1; -; Genomic_DNA.
DR EMBL; BT004743; AAO44009.1; -; mRNA.
DR EMBL; AY085335; AAM62566.1; -; mRNA.
DR PIR; T46120; T46120.
DR RefSeq; NP_001327913.1; NM_001339398.1.
DR RefSeq; NP_190479.1; NM_114769.4.
DR AlphaFoldDB; Q9SMU7; -.
DR SMR; Q9SMU7; -.
DR BioGRID; 9389; 5.
DR IntAct; Q9SMU7; 5.
DR STRING; 3702.AT3G49100.1; -.
DR PaxDb; Q9SMU7; -.
DR PRIDE; Q9SMU7; -.
DR ProteomicsDB; 226735; -.
DR EnsemblPlants; AT3G49100.1; AT3G49100.1; AT3G49100.
DR EnsemblPlants; AT3G49100.2; AT3G49100.2; AT3G49100.
DR GeneID; 824071; -.
DR Gramene; AT3G49100.1; AT3G49100.1; AT3G49100.
DR Gramene; AT3G49100.2; AT3G49100.2; AT3G49100.
DR KEGG; ath:AT3G49100; -.
DR Araport; AT3G49100; -.
DR TAIR; locus:2101288; AT3G49100.
DR eggNOG; KOG3465; Eukaryota.
DR HOGENOM; CLU_144337_2_0_1; -.
DR InParanoid; Q9SMU7; -.
DR OMA; YINSWEE; -.
DR OrthoDB; 1623953at2759; -.
DR PhylomeDB; Q9SMU7; -.
DR PRO; PR:Q9SMU7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SMU7; baseline and differential.
DR Genevisible; Q9SMU7; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IBA:GO_Central.
DR GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR GO; GO:0045900; P:negative regulation of translational elongation; IEA:InterPro.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IBA:GO_Central.
DR Gene3D; 3.30.720.10; -; 1.
DR InterPro; IPR008832; Signal_recog_particle_SRP9.
DR InterPro; IPR009018; Signal_recog_particle_SRP9/14.
DR InterPro; IPR039914; SRP9.
DR InterPro; IPR039432; SRP9_dom.
DR PANTHER; PTHR12834; PTHR12834; 1.
DR Pfam; PF05486; SRP9-21; 1.
DR PIRSF; PIRSF017029; Signal_recog_particle_SRP9; 1.
DR SUPFAM; SSF54762; SSF54762; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; RNA-binding;
KW Signal recognition particle.
FT CHAIN 1..103
FT /note="Signal recognition particle 9 kDa protein"
FT /id="PRO_0000135186"
FT REGION 81..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 103 AA; 12023 MW; 523525EC4656CF9C CRC64;
MVYIASWDEF VDRSVQLFRA DPESTRYVMK YRHCDGKLVL KVTDNKECLK FKTDQAQEAK
KMEKLNNIFF TLMARGPDVD LSEVTGKEQM ETQPAKKGRG RKQ
