ID   SRP09_CAEEL             Reviewed;          76 AA.
AC   P34642;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Signal recognition particle 9 kDa protein;
DE            Short=SRP9;
GN   ORFNames=ZK512.4;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC       ribonucleoprotein complex that mediates the cotranslational targeting
CC       of secretory and membrane proteins to the endoplasmic reticulum (ER)
CC       (By similarity). SRP9 together with SRP14 and the Alu portion of the
CC       SRP RNA, constitutes the elongation arrest domain of SRP (By
CC       similarity). The complex of SRP9 and SRP14 is required for SRP RNA
CC       binding (By similarity). {ECO:0000250|UniProtKB:P21262}.
CC   -!- SUBUNIT: Heterodimer with SRP14; binds RNA as heterodimer (By
CC       similarity). Component of a signal recognition particle complex that
CC       consists of a 7SL RNA molecule of 300 nucleotides and six protein
CC       subunits: srpa-72, srpa-68, SRP54, F37F2.2/SRP19, F25G6.8/SRP14 and
CC       ZK512.4/SRP9 (By similarity). {ECO:0000250|UniProtKB:P21262,
CC       ECO:0000250|UniProtKB:P49458}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SRP9 family. {ECO:0000305}.
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DR   EMBL; Z22177; CAA80148.1; -; Genomic_DNA.
DR   PIR; S40765; S40765.
DR   RefSeq; NP_499026.1; NM_066625.1.
DR   AlphaFoldDB; P34642; -.
DR   SMR; P34642; -.
DR   BioGRID; 41492; 1.
DR   IntAct; P34642; 1.
DR   STRING; 6239.ZK512.4; -.
DR   EPD; P34642; -.
DR   PaxDb; P34642; -.
DR   PeptideAtlas; P34642; -.
DR   EnsemblMetazoa; ZK512.4.1; ZK512.4.1; WBGene00013984.
DR   GeneID; 176293; -.
DR   KEGG; cel:CELE_ZK512.4; -.
DR   UCSC; ZK512.4; c. elegans.
DR   CTD; 176293; -.
DR   WormBase; ZK512.4; CE00410; WBGene00013984; -.
DR   eggNOG; KOG3465; Eukaryota.
DR   GeneTree; ENSGT00390000018505; -.
DR   HOGENOM; CLU_144337_3_0_1; -.
DR   InParanoid; P34642; -.
DR   OMA; YINSWEE; -.
DR   OrthoDB; 1623953at2759; -.
DR   PhylomeDB; P34642; -.
DR   Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   PRO; PR:P34642; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00013984; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IBA:GO_Central.
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0045900; P:negative regulation of translational elongation; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IBA:GO_Central.
DR   Gene3D; 3.30.720.10; -; 1.
DR   InterPro; IPR008832; Signal_recog_particle_SRP9.
DR   InterPro; IPR009018; Signal_recog_particle_SRP9/14.
DR   InterPro; IPR039914; SRP9.
DR   InterPro; IPR039432; SRP9_dom.
DR   PANTHER; PTHR12834; PTHR12834; 1.
DR   Pfam; PF05486; SRP9-21; 1.
DR   PIRSF; PIRSF017029; Signal_recog_particle_SRP9; 1.
DR   SUPFAM; SSF54762; SSF54762; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; RNA-binding;
KW   Signal recognition particle.
FT   CHAIN           1..76
FT                   /note="Signal recognition particle 9 kDa protein"
FT                   /id="PRO_0000135184"
SQ   SEQUENCE   76 AA;  8780 MW;  46520FE8A8FF77F7 CRC64;
     MTYFTSWDEF AKAAERLHSA NPEKCRFVTK YNHTKGQLVL KLTDDVVCLQ YSTNQLQDVK
     KLEKLSSTLL RGIVTQ