ID   SRP09_DICDI             Reviewed;          75 AA.
AC   Q55GL2;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Signal recognition particle 9 kDa protein;
DE            Short=SRP9;
GN   Name=srp9; ORFNames=DDB_G0267622;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC       ribonucleoprotein complex that mediates the cotranslational targeting
CC       of secretory and membrane proteins to the endoplasmic reticulum (ER)
CC       (By similarity). Srp9 together with srp14 and the Alu portion of the
CC       SRP RNA, constitutes the elongation arrest domain of SRP (By
CC       similarity). The complex of srp9 and srp14 is required for SRP RNA
CC       binding (By similarity). {ECO:0000250|UniProtKB:P21262}.
CC   -!- SUBUNIT: Heterodimer with srp14; binds RNA as heterodimer (By
CC       similarity). Component of a signal recognition particle complex that
CC       consists of a 7SL RNA molecule and six protein subunits: srp72, srp68,
CC       srp54, srp19, srp14 and srp9 (By similarity).
CC       {ECO:0000250|UniProtKB:P21262, ECO:0000250|UniProtKB:P49458}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SRP9 family. {ECO:0000305}.
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DR   EMBL; AAFI02000003; EAL73264.1; -; Genomic_DNA.
DR   RefSeq; XP_647172.1; XM_642080.1.
DR   AlphaFoldDB; Q55GL2; -.
DR   SMR; Q55GL2; -.
DR   STRING; 44689.DDB0232378; -.
DR   PaxDb; Q55GL2; -.
DR   EnsemblProtists; EAL73264; EAL73264; DDB_G0267622.
DR   GeneID; 8615975; -.
DR   KEGG; ddi:DDB_G0267622; -.
DR   dictyBase; DDB_G0267622; srp9.
DR   eggNOG; KOG3465; Eukaryota.
DR   HOGENOM; CLU_144337_3_0_1; -.
DR   InParanoid; Q55GL2; -.
DR   OMA; YINSWEE; -.
DR   PhylomeDB; Q55GL2; -.
DR   Reactome; R-DDI-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   PRO; PR:Q55GL2; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IBA:GO_Central.
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0045900; P:negative regulation of translational elongation; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IBA:GO_Central.
DR   Gene3D; 3.30.720.10; -; 1.
DR   InterPro; IPR008832; Signal_recog_particle_SRP9.
DR   InterPro; IPR009018; Signal_recog_particle_SRP9/14.
DR   InterPro; IPR039914; SRP9.
DR   InterPro; IPR039432; SRP9_dom.
DR   PANTHER; PTHR12834; PTHR12834; 1.
DR   Pfam; PF05486; SRP9-21; 1.
DR   PIRSF; PIRSF017029; Signal_recog_particle_SRP9; 1.
DR   SUPFAM; SSF54762; SSF54762; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; RNA-binding;
KW   Signal recognition particle.
FT   CHAIN           1..75
FT                   /note="Signal recognition particle 9 kDa protein"
FT                   /id="PRO_0000322234"
SQ   SEQUENCE   75 AA;  9290 MW;  9DD9337094A5A408 CRC64;
     MYIEDWDEFY DKSEQLYRTD PKRTRFSFKF RHVEGKVVLK VTNDTVNLKF QTDKENDFKR
     IDQINSLFFR LTTEQ