ID   SRP14_BOVIN             Reviewed;         110 AA.
AC   A6QQL9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Signal recognition particle 14 kDa protein;
DE            Short=SRP14;
GN   Name=SRP14;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal pons;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC       ribonucleoprotein complex that mediates the cotranslational targeting
CC       of secretory and membrane proteins to the endoplasmic reticulum (ER)
CC       (By similarity). SRP9 together with SRP14 and the Alu portion of the
CC       SRP RNA, constitutes the elongation arrest domain of SRP (By
CC       similarity). The complex of SRP9 and SRP14 is required for SRP RNA
CC       binding (By similarity). {ECO:0000250|UniProtKB:P37108}.
CC   -!- SUBUNIT: Heterodimer with SRP9; binds RNA as heterodimer (By
CC       similarity). Component of a signal recognition particle (SRP) complex
CC       that consists of a 7SL RNA molecule of 300 nucleotides and six protein
CC       subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9 (By similarity).
CC       {ECO:0000250|UniProtKB:P16255, ECO:0000250|UniProtKB:P37108}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SRP14 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC149893; AAI49894.1; -; mRNA.
DR   RefSeq; NP_001093820.1; NM_001100350.1.
DR   AlphaFoldDB; A6QQL9; -.
DR   SMR; A6QQL9; -.
DR   STRING; 9913.ENSBTAP00000019085; -.
DR   PaxDb; A6QQL9; -.
DR   PRIDE; A6QQL9; -.
DR   Ensembl; ENSBTAT00000019085; ENSBTAP00000019085; ENSBTAG00000014353.
DR   GeneID; 512792; -.
DR   KEGG; bta:512792; -.
DR   CTD; 6727; -.
DR   VEuPathDB; HostDB:ENSBTAG00000014353; -.
DR   VGNC; VGNC:35284; SRP14.
DR   eggNOG; KOG1761; Eukaryota.
DR   GeneTree; ENSGT00390000008496; -.
DR   HOGENOM; CLU_094309_2_1_1; -.
DR   InParanoid; A6QQL9; -.
DR   OMA; RFNGHNK; -.
DR   OrthoDB; 1634105at2759; -.
DR   TreeFam; TF106247; -.
DR   Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-BTA-6798695; Neutrophil degranulation.
DR   Proteomes; UP000009136; Chromosome 10.
DR   Bgee; ENSBTAG00000014353; Expressed in oocyte and 106 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IBA:GO_Central.
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0030942; F:endoplasmic reticulum signal peptide binding; IEA:InterPro.
DR   GO; GO:0045047; P:protein targeting to ER; IBA:GO_Central.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR   Gene3D; 3.30.720.10; -; 1.
DR   InterPro; IPR003210; Signal_recog_particle_SRP14.
DR   InterPro; IPR009018; Signal_recog_particle_SRP9/14.
DR   PANTHER; PTHR12013; PTHR12013; 1.
DR   Pfam; PF02290; SRP14; 1.
DR   SUPFAM; SSF54762; SSF54762; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Phosphoprotein; Reference proteome; Ribonucleoprotein;
KW   RNA-binding; Signal recognition particle.
FT   CHAIN           1..110
FT                   /note="Signal recognition particle 14 kDa protein"
FT                   /id="PRO_0000322235"
FT   REGION          90..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         45
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P16254"
SQ   SEQUENCE   110 AA;  12461 MW;  0D01C5A392082FD9 CRC64;
     MVLLESEQFL TELTRLFQKC RLSGSVFITL KKYDGRTKPI PRKGSVEGFE PSDNKCLLRA
     TDGKKKISTV VSSKEVNKFQ MAYSNLLRAN MDGLKKRDKK SKSKKSKAAQ