ID   SRP14_MACRA             Reviewed;          74 AA.
AC   O18881;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Signal recognition particle 14 kDa protein;
DE            Short=SRP14;
DE   Flags: Fragment;
GN   Name=SRP14; Synonyms=SRP14A;
OS   Macaca radiata (Bonnet macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9548;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Ganesh S., Saleem Q., Brahmachari S.K.;
RT   "Partial sequence of the signal recognition particle gene (SRP) from the
RT   bonnet monkey, Macaca radiata.";
RL   Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC       ribonucleoprotein complex that mediates the cotranslational targeting
CC       of secretory and membrane proteins to the endoplasmic reticulum (ER)
CC       (By similarity). SRP9 together with SRP14 and the Alu portion of the
CC       SRP RNA, constitutes the elongation arrest domain of SRP (By
CC       similarity). The complex of SRP9 and SRP14 is required for SRP RNA
CC       binding (By similarity). {ECO:0000250|UniProtKB:P37108}.
CC   -!- SUBUNIT: Heterodimer with SRP9; binds RNA as heterodimer (By
CC       similarity). Component of a signal recognition particle (SRP) complex
CC       that consists of a 7SL RNA molecule of 300 nucleotides and six protein
CC       subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9 (By similarity).
CC       {ECO:0000250|UniProtKB:P16255, ECO:0000250|UniProtKB:P37108}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the SRP14 family. {ECO:0000305}.
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DR   EMBL; AF027404; AAB86815.1; -; Genomic_DNA.
DR   AlphaFoldDB; O18881; -.
DR   SMR; O18881; -.
DR   GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-KW.
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0030942; F:endoplasmic reticulum signal peptide binding; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR   Gene3D; 3.30.720.10; -; 1.
DR   InterPro; IPR003210; Signal_recog_particle_SRP14.
DR   InterPro; IPR009018; Signal_recog_particle_SRP9/14.
DR   PANTHER; PTHR12013; PTHR12013; 1.
DR   Pfam; PF02290; SRP14; 1.
DR   SUPFAM; SSF54762; SSF54762; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Ribonucleoprotein; RNA-binding; Signal recognition particle.
FT   CHAIN           <1..74
FT                   /note="Signal recognition particle 14 kDa protein"
FT                   /id="PRO_0000135190"
FT   NON_TER         1
SQ   SEQUENCE   74 AA;  7376 MW;  77E43C3602ABE8D8 CRC64;
     STVVSSKEVN KFQMAYSNLL RANMDGLKKR DKKNKTKKTK AAAAAAAAAV AAAAAPTAAA
     TTATPATPAA TAAQ