ID   SRP14_PONAB             Reviewed;         136 AA.
AC   Q5RBX7;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Signal recognition particle 14 kDa protein;
DE            Short=SRP14;
GN   Name=SRP14;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC       ribonucleoprotein complex that mediates the cotranslational targeting
CC       of secretory and membrane proteins to the endoplasmic reticulum (ER)
CC       (By similarity). SRP9 together with SRP14 and the Alu portion of the
CC       SRP RNA, constitutes the elongation arrest domain of SRP (By
CC       similarity). The complex of SRP9 and SRP14 is required for SRP RNA
CC       binding (By similarity). {ECO:0000250|UniProtKB:P37108}.
CC   -!- SUBUNIT: Heterodimer with SRP9; binds RNA as heterodimer (By
CC       similarity). Component of a signal recognition particle (SRP) complex
CC       that consists of a 7SL RNA molecule of 300 nucleotides and six protein
CC       subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9 (By similarity).
CC       {ECO:0000250|UniProtKB:P16255, ECO:0000250|UniProtKB:P37108}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SRP14 family. {ECO:0000305}.
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DR   EMBL; CR858505; CAH90733.1; -; mRNA.
DR   RefSeq; NP_001125409.1; NM_001131937.1.
DR   AlphaFoldDB; Q5RBX7; -.
DR   SMR; Q5RBX7; -.
DR   STRING; 9601.ENSPPYP00000007182; -.
DR   PRIDE; Q5RBX7; -.
DR   GeneID; 100172315; -.
DR   KEGG; pon:100172315; -.
DR   CTD; 6727; -.
DR   eggNOG; KOG1761; Eukaryota.
DR   HOGENOM; CLU_094309_2_1_1; -.
DR   InParanoid; Q5RBX7; -.
DR   OrthoDB; 1634105at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-KW.
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0030942; F:endoplasmic reticulum signal peptide binding; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR   Gene3D; 3.30.720.10; -; 1.
DR   InterPro; IPR003210; Signal_recog_particle_SRP14.
DR   InterPro; IPR009018; Signal_recog_particle_SRP9/14.
DR   PANTHER; PTHR12013; PTHR12013; 1.
DR   Pfam; PF02290; SRP14; 1.
DR   SUPFAM; SSF54762; SSF54762; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Phosphoprotein; Reference proteome; Ribonucleoprotein;
KW   RNA-binding; Signal recognition particle.
FT   CHAIN           1..136
FT                   /note="Signal recognition particle 14 kDa protein"
FT                   /id="PRO_0000322237"
FT   MOD_RES         27
FT                   /note="Phosphotyrosine"
FT                   /evidence="ECO:0000250|UniProtKB:P37108"
SQ   SEQUENCE   136 AA;  14544 MW;  2B5B2D1D77BA5E8E CRC64;
     MVLLESEQFL TELTRLFQKC RTSGSVYITL KKYDGRTKPI PKKGTVEGFE PADNKCLLRA
     TDGKKKISTV VSSKEVNKFQ MAYSNLLRAN MDGLKKRDKK NKTKKTKAAA AAAAAAPAAA
     ATAATTAATT AATAAQ