SRP19_HALSA
ID SRP19_HALSA Reviewed; 92 AA.
AC Q9HQ21;
DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2001, sequence version 1.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=Signal recognition particle 19 kDa protein {ECO:0000255|HAMAP-Rule:MF_00305};
DE Short=SRP19 {ECO:0000255|HAMAP-Rule:MF_00305};
GN Name=srp19 {ECO:0000255|HAMAP-Rule:MF_00305}; OrderedLocusNames=VNG_1367G;
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=64091;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- FUNCTION: Involved in targeting and insertion of nascent membrane
CC proteins into the cytoplasmic membrane. Binds directly to 7S RNA and
CC mediates binding of the 54 kDa subunit of the SRP. {ECO:0000255|HAMAP-
CC Rule:MF_00305}.
CC -!- SUBUNIT: Part of the signal recognition particle protein translocation
CC system, which is composed of SRP and FtsY. Archaeal SRP consists of a
CC 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and
CC SRP19. {ECO:0000255|HAMAP-Rule:MF_00305}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00305}.
CC -!- SIMILARITY: Belongs to the SRP19 family. {ECO:0000255|HAMAP-
CC Rule:MF_00305}.
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DR EMBL; AE004437; AAG19696.1; -; Genomic_DNA.
DR PIR; D84291; D84291.
DR RefSeq; WP_010902992.1; NC_002607.1.
DR AlphaFoldDB; Q9HQ21; -.
DR SMR; Q9HQ21; -.
DR STRING; 64091.VNG_1367G; -.
DR PaxDb; Q9HQ21; -.
DR EnsemblBacteria; AAG19696; AAG19696; VNG_1367G.
DR GeneID; 5953771; -.
DR KEGG; hal:VNG_1367G; -.
DR PATRIC; fig|64091.14.peg.1044; -.
DR HOGENOM; CLU_169299_1_0_2; -.
DR InParanoid; Q9HQ21; -.
DR OMA; VIWPAYL; -.
DR OrthoDB; 121943at2157; -.
DR PhylomeDB; Q9HQ21; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0048500; C:signal recognition particle; IEA:UniProtKB-UniRule.
DR GO; GO:0008312; F:7S RNA binding; IBA:GO_Central.
DR GO; GO:0006617; P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; IBA:GO_Central.
DR Gene3D; 3.30.56.30; -; 1.
DR HAMAP; MF_00305; SRP19; 1.
DR InterPro; IPR002778; Signal_recog_particle_SRP19.
DR InterPro; IPR036521; SRP19-like_sf.
DR InterPro; IPR022938; SRP19_arc-type.
DR PANTHER; PTHR17453; PTHR17453; 1.
DR Pfam; PF01922; SRP19; 1.
DR SUPFAM; SSF69695; SSF69695; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; RNA-binding;
KW Signal recognition particle.
FT CHAIN 1..92
FT /note="Signal recognition particle 19 kDa protein"
FT /id="PRO_0000135215"
SQ SEQUENCE 92 AA; 10213 MW; 20F25A909218DCC5 CRC64;
MVENVIWPAY FDAALSRRDG RRVPMELAVE EPSIDEIATA VQQVGYDAVV ERDVAYPRRH
WDAAGRVLVK DADDAKNTLV QAVAAYVGAL RD