ID   SRP19_METAC             Reviewed;         101 AA.
AC   Q8TTY3;
DT   19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2002, sequence version 2.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Signal recognition particle 19 kDa protein {ECO:0000255|HAMAP-Rule:MF_00305};
DE            Short=SRP19 {ECO:0000255|HAMAP-Rule:MF_00305};
GN   Name=srp19 {ECO:0000255|HAMAP-Rule:MF_00305}; OrderedLocusNames=MA_0292;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- FUNCTION: Involved in targeting and insertion of nascent membrane
CC       proteins into the cytoplasmic membrane. Binds directly to 7S RNA and
CC       mediates binding of the 54 kDa subunit of the SRP. {ECO:0000255|HAMAP-
CC       Rule:MF_00305}.
CC   -!- SUBUNIT: Part of the signal recognition particle protein translocation
CC       system, which is composed of SRP and FtsY. Archaeal SRP consists of a
CC       7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and
CC       SRP19. {ECO:0000255|HAMAP-Rule:MF_00305}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00305}.
CC   -!- SIMILARITY: Belongs to the SRP19 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAM03745.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE010299; AAM03745.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_048066074.1; NC_003552.1.
DR   AlphaFoldDB; Q8TTY3; -.
DR   SMR; Q8TTY3; -.
DR   STRING; 188937.MA_0292; -.
DR   PRIDE; Q8TTY3; -.
DR   EnsemblBacteria; AAM03745; AAM03745; MA_0292.
DR   GeneID; 1472184; -.
DR   KEGG; mac:MA_0292; -.
DR   HOGENOM; CLU_169299_1_0_2; -.
DR   InParanoid; Q8TTY3; -.
DR   OMA; VIWPAYL; -.
DR   OrthoDB; 121943at2157; -.
DR   PhylomeDB; Q8TTY3; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0048500; C:signal recognition particle; IEA:UniProtKB-UniRule.
DR   GO; GO:0008312; F:7S RNA binding; IBA:GO_Central.
DR   GO; GO:0006617; P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; IBA:GO_Central.
DR   Gene3D; 3.30.56.30; -; 1.
DR   HAMAP; MF_00305; SRP19; 1.
DR   InterPro; IPR002778; Signal_recog_particle_SRP19.
DR   InterPro; IPR036521; SRP19-like_sf.
DR   InterPro; IPR022938; SRP19_arc-type.
DR   PANTHER; PTHR17453; PTHR17453; 1.
DR   Pfam; PF01922; SRP19; 1.
DR   SUPFAM; SSF69695; SSF69695; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; RNA-binding;
KW   Signal recognition particle.
FT   CHAIN           1..101
FT                   /note="Signal recognition particle 19 kDa protein"
FT                   /id="PRO_0000135216"
SQ   SEQUENCE   101 AA;  11415 MW;  8DA2E31AAA9594C3 CRC64;
     MKDKGKLVIW PAYIDQTRSR SNGRIISRKN AVKEPHLNEI KDAAKNLGLN PEVEPEKAYP
     KSWWEVSGRV LVDDRGPKSV IAKQISLEIR KKRGKGVPAK T