SRPE_CHLTH
ID SRPE_CHLTH Reviewed; 151 AA.
AC P26757;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Sulfur-rich protein, serovar E;
DE AltName: Full=15 kDa cysteine-rich outer membrane protein;
DE AltName: Full=Cysteine-rich protein A;
GN Name=srp; Synonyms=crpA;
OS Chlamydia trachomatis.
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=813;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=BOUR / Serovar E;
RX PubMed=1997423; DOI=10.1128/iai.59.3.1196-1201.1991;
RA de la Maza L.M., Fiedler T.J., Carlson E.J., Markoff B.A., Peterson E.M.;
RT "Sequence diversity of the 60-kilodalton protein and of a putative 15-
RT kilodalton protein between the trachoma and lymphogranuloma venereum
RT biovars of Chlamydia trachomatis.";
RL Infect. Immun. 59:1196-1201(1991).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}. Note=Immunolocalizes to the inclusion membrane,
CC the membrane that surrounds the intracellular parasite. This protein is
CC recognized by CD8+ T-cells in both human and mouse infections,
CC suggesting it gains access to the host cytoplasm. {ECO:0000250}.
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DR EMBL; X54389; CAA38260.1; -; Genomic_DNA.
DR PIR; E43584; E43584.
DR RefSeq; WP_009873135.1; NZ_JPNM01000003.1.
DR AlphaFoldDB; P26757; -.
DR OMA; VFMEKPC; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR InterPro; IPR008436; CRPA.
DR Pfam; PF05745; CRPA; 1.
PE 3: Inferred from homology;
KW Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..151
FT /note="Sulfur-rich protein, serovar E"
FT /id="PRO_0000207124"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 151 AA; 16020 MW; C6CA7DFB8FC0C354 CRC64;
MSTVPVVQGA GSSNSAQDIS TSSAPLTLKE RISNLLSSTA FKVGLVVIGL LLVITALIFL
VSAASFVNAI YLGIPAILGC VNICVGILSI EGHCSPERWI LCKKVLKTSE DIIDDGQINN
SNKVFTDERL NAMDGVVESL SRRNSLVDQT Q