ID   SRPH_SYNE7              Reviewed;         319 AA.
AC   Q59967; Q7BA85;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Serine acetyltransferase, plasmid;
DE            Short=SAT;
DE            EC=2.3.1.30;
GN   Name=srpH; OrderedLocusNames=Synpcc7942_B2663; ORFNames=pANL39;
OS   Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans
OS   R2).
OG   Plasmid pANL.
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=1140;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION BY SULFUR STARVATION.
RC   STRAIN=PCC 7942 / FACHB-805; PLASMID=pANL;
RX   PubMed=7603442; DOI=10.1007/bf00290354;
RA   Nicholson M.L., Gaasenbeek M., Laudenbach D.E.;
RT   "Two enzymes together capable of cysteine biosynthesis are encoded on a
RT   cyanobacterial plasmid.";
RL   Mol. Gen. Genet. 247:623-632(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805; PLASMID=pANL;
RA   Holtman C.K., Chen Y., Sandoval P., Socias T., Mohler B.J., Youderian P.,
RA   Golden S.S.;
RT   "pANL, the large plasmid of Synechococcus elongatus PCC 7942.";
RL   Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805; PLASMID=pANL;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of plasmid 1 of Synechococcus elongatus PCC 7942.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + L-serine = CoA + O-acetyl-L-serine;
CC         Xref=Rhea:RHEA:24560, ChEBI:CHEBI:33384, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288, ChEBI:CHEBI:58340; EC=2.3.1.30;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine
CC       from L-serine: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- INDUCTION: Transcriptionally induced in the absence of sulfur, requires
CC       CysR for transcription. Part of the srpG-srpH-srpI operon.
CC       {ECO:0000269|PubMed:7603442}.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000305}.
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DR   EMBL; U23436; AAA86726.1; -; Genomic_DNA.
DR   EMBL; AF441790; AAM81165.1; -; Genomic_DNA.
DR   EMBL; CP000101; ABB58692.1; -; Genomic_DNA.
DR   RefSeq; NP_665778.1; NC_004073.2.
DR   RefSeq; WP_011055155.1; NC_007595.1.
DR   AlphaFoldDB; Q59967; -.
DR   SMR; Q59967; -.
DR   STRING; 1140.Synpcc7942_B2663; -.
DR   PRIDE; Q59967; -.
DR   EnsemblBacteria; ABB58692; ABB58692; Synpcc7942_B2663.
DR   KEGG; syf:Synpcc7942_B2663; -.
DR   eggNOG; COG1045; Bacteria.
DR   HOGENOM; CLU_051638_1_0_3; -.
DR   OMA; WAMTHHR; -.
DR   OrthoDB; 1639008at2; -.
DR   BioCyc; SYNEL:SYNPCC7942_B2663-MON; -.
DR   UniPathway; UPA00136; UER00199.
DR   GO; GO:0031470; C:carboxysome; IEA:UniProt.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009001; F:serine O-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043886; F:structural constituent of carboxysome; IEA:UniProt.
DR   GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd03354; LbH_SAT; 1.
DR   Gene3D; 1.10.3130.10; -; 1.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR045304; LbH_SAT.
DR   InterPro; IPR042122; Ser_AcTrfase_N_sf.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
PE   2: Evidence at transcript level;
KW   Acyltransferase; Amino-acid biosynthesis; Cysteine biosynthesis; Cytoplasm;
KW   Plasmid; Repeat; Transferase.
FT   CHAIN           1..319
FT                   /note="Serine acetyltransferase, plasmid"
FT                   /id="PRO_0000068688"
SQ   SEQUENCE   319 AA;  34570 MW;  00BB74D8AABB1E70 CRC64;
     MSLSPRSDRT EIRRSWGLDS IVSALSQAST DPLPHHLLSD QFYPLPSRES LGLILHGLRS
     VLFPRHFGDP ELSVETTHYF IGNTLDKTLN LLNEQIRREL WLQHVTQGTP EATPAVLSQH
     ASELTQAFAQ ALPEIKRLLD SDVNAAYLGD PAAQSISEIL FCYPGITAIT FHRLAHRLYQ
     LGLPLLARIT AEVSHSETGI DIHPGAAIGG SFFIDHGTGV VIGETCVIGD RVRIYQAVTL
     GAKSFPRDET GALIKGQARH PVIEDDVVIY AGATLLGRIT VGRGSTIGGN VWLTRSVPAG
     SFISQAQIRS DNFESGGGI