SRP_CHLTA
ID SRP_CHLTA Reviewed; 152 AA.
AC Q3KLQ8;
DT 05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Sulfur-rich protein;
DE AltName: Full=Cysteine-rich protein A;
GN Name=srp; Synonyms=crpA; OrderedLocusNames=CTA_0482;
OS Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=315277;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC VR-571B / DSM 19440 / HAR-13;
RX PubMed=16177312; DOI=10.1128/iai.73.10.6407-6418.2005;
RA Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D.;
RT "Comparative genomic analysis of Chlamydia trachomatis oculotropic and
RT genitotropic strains.";
RL Infect. Immun. 73:6407-6418(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}. Note=Immunolocalizes to the inclusion membrane,
CC the membrane that surrounds the intracellular parasite. This protein is
CC recognized by CD8+ T-cells in both human and mouse infections,
CC suggesting it gains access to the host cytoplasm. {ECO:0000250}.
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DR EMBL; CP000051; AAX50714.1; -; Genomic_DNA.
DR RefSeq; WP_011324736.1; NC_007429.1.
DR AlphaFoldDB; Q3KLQ8; -.
DR SMR; Q3KLQ8; -.
DR EnsemblBacteria; AAX50714; AAX50714; CTA_0482.
DR KEGG; cta:CTA_0482; -.
DR HOGENOM; CLU_1737288_0_0_0; -.
DR OMA; VFMEKPC; -.
DR Proteomes; UP000002532; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR InterPro; IPR008436; CRPA.
DR Pfam; PF05745; CRPA; 1.
PE 3: Inferred from homology;
KW Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..152
FT /note="Sulfur-rich protein"
FT /id="PRO_0000248633"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 152 AA; 16133 MW; 31D325CC0619A2F1 CRC64;
MSTVPVVQGA GSSNSAQDIS TSSAPLTLKE RISNLLSSTA FKVGLVVIGL LLVIATLIFL
VSAASFVNAI YLVAIPAILG CVNICVGILS MEGHCSPERW ILCKKVLKTS EDIIDDGQIN
NSNKVFTDER LNAIDGVVES LSRRNSLVDQ TQ