SRR1_ARATH
ID SRR1_ARATH Reviewed; 275 AA.
AC Q8GWZ6; Q9LTH5;
DT 30-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2003, sequence version 2.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Protein SENSITIVITY TO RED LIGHT REDUCED 1;
GN Name=SRR1; OrderedLocusNames=At5g59560; ORFNames=F2O15.220, F2O15.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, AND INDUCTION.
RC STRAIN=cv. Columbia;
RX PubMed=12533513; DOI=10.1101/gad.244103;
RA Staiger D., Allenbach L., Salathia N., Fiechter V., Davis S.J.,
RA Millar A.J., Chory J., Fankhauser C.;
RT "The Arabidopsis SRR1 gene mediates phyB signaling and is required for
RT normal circadian clock function.";
RL Genes Dev. 17:256-268(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 206-275.
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
CC -!- FUNCTION: Probable regulator involved in a circadian clock input
CC pathway, which is required for normal oscillator function. Regulates
CC the expression of clock-regulated genes such as CCA1 and TOC1. Involved
CC in both the phytochrome B (PHYB) and PHYB-independent signaling
CC pathways. {ECO:0000269|PubMed:12533513}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12533513}. Nucleus
CC {ECO:0000269|PubMed:12533513}.
CC -!- INDUCTION: By light. Not modulated by far-red light.
CC {ECO:0000269|PubMed:12533513}.
CC -!- SIMILARITY: Belongs to the SRR1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC43135.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AY127047; AAM97478.1; -; mRNA.
DR EMBL; AB025604; BAA97490.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97205.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97206.1; -; Genomic_DNA.
DR EMBL; AY084714; AAM61288.1; -; mRNA.
DR EMBL; AK118532; BAC43135.1; ALT_INIT; mRNA.
DR RefSeq; NP_200764.1; NM_125348.4.
DR RefSeq; NP_851224.1; NM_180893.2.
DR AlphaFoldDB; Q8GWZ6; -.
DR BioGRID; 21319; 1.
DR STRING; 3702.AT5G59560.2; -.
DR iPTMnet; Q8GWZ6; -.
DR PaxDb; Q8GWZ6; -.
DR PRIDE; Q8GWZ6; -.
DR ProteomicsDB; 226562; -.
DR EnsemblPlants; AT5G59560.1; AT5G59560.1; AT5G59560.
DR EnsemblPlants; AT5G59560.2; AT5G59560.2; AT5G59560.
DR GeneID; 836075; -.
DR Gramene; AT5G59560.1; AT5G59560.1; AT5G59560.
DR Gramene; AT5G59560.2; AT5G59560.2; AT5G59560.
DR KEGG; ath:AT5G59560; -.
DR Araport; AT5G59560; -.
DR TAIR; locus:2148333; AT5G59560.
DR eggNOG; KOG3131; Eukaryota.
DR HOGENOM; CLU_062516_1_0_1; -.
DR InParanoid; Q8GWZ6; -.
DR OMA; SWHFFKL; -.
DR OrthoDB; 1590454at2759; -.
DR PhylomeDB; Q8GWZ6; -.
DR PRO; PR:Q8GWZ6; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8GWZ6; baseline and differential.
DR Genevisible; Q8GWZ6; AT.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0007623; P:circadian rhythm; IMP:UniProtKB.
DR GO; GO:0007017; P:microtubule-based process; IBA:GO_Central.
DR GO; GO:0010017; P:red or far-red light signaling pathway; IMP:UniProtKB.
DR GO; GO:0009585; P:red, far-red light phototransduction; IMP:TAIR.
DR GO; GO:0042752; P:regulation of circadian rhythm; IMP:TAIR.
DR InterPro; IPR012942; SRR1-like.
DR InterPro; IPR040044; SRR1L.
DR PANTHER; PTHR28626; PTHR28626; 1.
DR Pfam; PF07985; SRR1; 1.
PE 2: Evidence at transcript level;
KW Biological rhythms; Cytoplasm; Nucleus; Phytochrome signaling pathway;
KW Reference proteome.
FT CHAIN 1..275
FT /note="Protein SENSITIVITY TO RED LIGHT REDUCED 1"
FT /id="PRO_0000186122"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 26..29
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT COMPBIAS 31..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 207
FT /note="G -> V (in Ref. 5)"
FT /evidence="ECO:0000305"
FT CONFLICT 209..210
FT /note="SF -> RS (in Ref. 5)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 275 AA; 31475 MW; 4FBE65C784CFFB4E CRC64;
METTVKNSSS DGEWKVVLPS KGRQGRRRKP KPKGQAEEEE QPWKSDDLEI DPQRQARLKQ
KMEISLKKIE SSSFYTAFLE QLKSPEVSNQ IRLVLGSETQ LQMVMYGIGS IESYESPRFQ
LSIAILMKRE FDWVGDNIEV FDPVLSATES SYLESLGCSV LSVNEQARRE ALKPTLFFMP
HCEANLYSNL LQANWRMDRL SKIALFGNSF QMYEEQVSFD AEVICATKRI IAAQRVTSEF
AIETESDDYF AAFHDSSWHF FSSGIDSELP LFVSD
