SRRM1_CHICK
ID SRRM1_CHICK Reviewed; 888 AA.
AC Q5ZMJ9;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Serine/arginine repetitive matrix protein 1;
GN Name=SRRM1; ORFNames=RCJMB04_1m21;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Involved in pre-mRNA splicing and processing events.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00627}.
CC -!- SIMILARITY: Belongs to the splicing factor SR family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ719385; CAG31044.1; -; mRNA.
DR RefSeq; NP_001026665.1; NM_001031494.1.
DR AlphaFoldDB; Q5ZMJ9; -.
DR BMRB; Q5ZMJ9; -.
DR SMR; Q5ZMJ9; -.
DR STRING; 9031.ENSGALP00000001957; -.
DR PaxDb; Q5ZMJ9; -.
DR PRIDE; Q5ZMJ9; -.
DR GeneID; 428216; -.
DR KEGG; gga:428216; -.
DR CTD; 10250; -.
DR VEuPathDB; HostDB:geneid_428216; -.
DR eggNOG; KOG2146; Eukaryota.
DR InParanoid; Q5ZMJ9; -.
DR OrthoDB; 1210775at2759; -.
DR PhylomeDB; Q5ZMJ9; -.
DR PRO; PR:Q5ZMJ9; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR002483; PWI_dom.
DR InterPro; IPR036483; PWI_dom_sf.
DR Pfam; PF01480; PWI; 1.
DR SMART; SM00311; PWI; 1.
DR SUPFAM; SSF101233; SSF101233; 1.
DR PROSITE; PS51025; PWI; 1.
PE 2: Evidence at transcript level;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT CHAIN 1..888
FT /note="Serine/arginine repetitive matrix protein 1"
FT /id="PRO_0000076329"
FT DOMAIN 27..126
FT /note="PWI"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00627"
FT REGION 139..888
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..205
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..345
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..412
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..526
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..548
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..564
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..619
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 724..748
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..791
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..824
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..879
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 888 AA; 100804 MW; 203724AEAAE4B465 CRC64;
MDAGFFRGTS AEQDNRFSNK QKKLLKQLKF AECLEKKVDM SKVNLEVIKP WITKRVTEIL
GFEDDVVIEF IFNQLEVKNP DSKMMQINLT GFLNGKNARE FMGELWPLLL SAQENIAGIP
TAFLELKKEE IKQRQIEQEK LASMKKQDED KEKRDKEDKD NREKRDRSRS PRRRKSRSPS
PRRRSSPIRR ERKRSHSRSP HHRTKSRSAT PAPEKKEATP EPEPSVKPKE TVVQEATSNS
DIPKAPKSEP PVPETKEISP ERNSKKEREK EKEKTRQRSP TRSKSRSRSR SRSPSHSRPR
RRHRSRSRRR PSPRRRPSPR RRTPPRRMPP PPRHRRSRSP VRRRRRSSAS LSGSSSSSSS
SRSRSPPKKP PKRTVSSPPR KTRRLSPSAS PPRRRHRPSP PASPPPKPRR SPTPQQSNRA
RKSRGSVSPG RASAPKHKST EKRESPSPAP KPRKAELSES EEDKGGKMAA ADSVQQRRQY
RRQNQQSSSD SGSSSSSEEE RPKRSNVKNG EVGRRRRHSH SRSPSPSPRK RQKEPSPRRR
RRSPSPPPAR RRRSPSPPPP PRRRRSPSLP RRRSPSPPPR RRSPSPRRYS PPIQRRYSPS
PPPKRRTASP PPPPKRRASP SPQSKRRVSH SPPPKQRSSP AAKRRSPSIS SKHRKGSPPS
RSNRETRSPP QNKRDSPSPR PRASHTSSSP PPLRRGASAS PQRRQSPSPS TRPIRRVSRT
PEPKKTKAST PSPRSARRVS SSRSASGSPE PAPKKHQGPP SPARSRSPSA NWSPAKKAKS
PTQSPSPARN SDQEGGGKKK KKKKDKKHKK DKKHKKHKKH KKEKAAVAAA PAAVAAADTT
SAQEEQEAET EPKKETESEP EDNLDDLEKH LREKALRSMR KAQVSPPS
