位置:首页 > 蛋白库 > SRS6_ARATH
SRS6_ARATH
ID   SRS6_ARATH              Reviewed;         183 AA.
AC   Q9M2U4;
DT   11-DEC-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Protein SHI RELATED SEQUENCE 6;
GN   Name=SRS6; OrderedLocusNames=At3g54430; ORFNames=T12E18.120;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA   Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA   Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA   Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA   Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA   Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA   Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA   Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16740146; DOI=10.1111/j.1365-313x.2006.02774.x;
RA   Kuusk S., Sohlberg J.J., Magnus Eklund D., Sundberg E.;
RT   "Functionally redundant SHI family genes regulate Arabidopsis gynoecium
RT   development in a dose-dependent manner.";
RL   Plant J. 47:99-111(2006).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=21976484; DOI=10.1104/pp.111.182253;
RA   Eklund D.M., Cierlik I., Staaldal V., Claes A.R., Vestman D., Chandler J.,
RA   Sundberg E.;
RT   "Expression of Arabidopsis SHORT INTERNODES/STYLISH family genes in auxin
RT   biosynthesis zones of aerial organs is dependent on a GCC box-like
RT   regulatory element.";
RL   Plant Physiol. 157:2069-2080(2011).
CC   -!- FUNCTION: Transcription activator that binds DNA on 5'-ACTCTAC-3' and
CC       promotes auxin homeostasis-regulating gene expression (e.g. YUC genes),
CC       as well as genes affecting stamen development, cell expansion and
CC       timing of flowering. Synergistically with other SHI-related proteins,
CC       regulates gynoecium, stamen and leaf development in a dose-dependent
CC       manner, controlling apical-basal patterning. Promotes style and stigma
CC       formation, and influences vascular development during gynoecium
CC       development. May also have a role in the formation and/or maintenance
CC       of the shoot apical meristem (SAM) (By similarity). {ECO:0000250}.
CC   -!- INTERACTION:
CC       Q9M2U4; Q9SI19: SRS4; NbExp=4; IntAct=EBI-15201394, EBI-15193733;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SHI protein family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL132971; CAB81808.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE79229.1; -; Genomic_DNA.
DR   EMBL; AF446889; AAL38622.1; -; mRNA.
DR   EMBL; AY052675; AAK96579.1; -; mRNA.
DR   PIR; T47602; T47602.
DR   RefSeq; NP_191011.1; NM_115303.2.
DR   AlphaFoldDB; Q9M2U4; -.
DR   BioGRID; 9925; 9.
DR   IntAct; Q9M2U4; 6.
DR   STRING; 3702.AT3G54430.1; -.
DR   PaxDb; Q9M2U4; -.
DR   PRIDE; Q9M2U4; -.
DR   EnsemblPlants; AT3G54430.1; AT3G54430.1; AT3G54430.
DR   GeneID; 824609; -.
DR   Gramene; AT3G54430.1; AT3G54430.1; AT3G54430.
DR   KEGG; ath:AT3G54430; -.
DR   Araport; AT3G54430; -.
DR   TAIR; locus:2096169; AT3G54430.
DR   eggNOG; ENOG502SJSF; Eukaryota.
DR   HOGENOM; CLU_041493_3_0_1; -.
DR   InParanoid; Q9M2U4; -.
DR   OMA; ECSFERC; -.
DR   OrthoDB; 1262400at2759; -.
DR   PhylomeDB; Q9M2U4; -.
DR   PRO; PR:Q9M2U4; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9M2U4; differential.
DR   Genevisible; Q9M2U4; AT.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009851; P:auxin biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR   InterPro; IPR007818; SHI.
DR   InterPro; IPR006511; SHI_C.
DR   InterPro; IPR006510; Znf_LRP1.
DR   PANTHER; PTHR31604; PTHR31604; 1.
DR   TIGRFAMs; TIGR01624; LRP1_Cterm; 1.
DR   TIGRFAMs; TIGR01623; put_zinc_LRP1; 1.
PE   1: Evidence at protein level;
KW   Activator; Auxin biosynthesis; Auxin signaling pathway;
KW   Developmental protein; DNA-binding; Metal-binding; Nucleus;
KW   Reference proteome; Zinc.
FT   CHAIN           1..183
FT                   /note="Protein SHI RELATED SEQUENCE 6"
FT                   /id="PRO_0000424578"
FT   DNA_BIND        41..68
FT                   /note="Zn(2)-C6 fungal-type; degenerate"
FT                   /evidence="ECO:0000250"
FT   REGION          79..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           157..160
FT                   /note="Required for homo- and heterodimerization"
FT                   /evidence="ECO:0000250"
FT   COMPBIAS        100..117
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         41
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         41
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         44
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         52
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         57
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         57
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         61
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         68
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   183 AA;  20326 MW;  EAE36E542EA31221 CRC64;
     MLGLRNIILL SPPPTQITRP SLPPVNFAAV EDNNTVGEKV CRDCGNRAKK ECLFERCRTC
     CKSRGYNCVT HVKSTWIPSS ATRSSSSPSE RKKKLKIDKQ SSPNVSLLPT TTSRQERGFR
     EGLPGKIEAP AVFKRTRVTA ISNNEQAEIG YQATVTISGH IFKGFLHYYG VDHNKAFPCL
     SQK
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024