ID   SRTF_STRPY              Reviewed;         229 AA.
AC   P0C0E2; Q9FDU7;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Lantibiotic transport ATP-binding protein SrtF;
GN   Name=srtF;
OS   Streptococcus pyogenes.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BL-T;
RX   PubMed=11328600; DOI=10.1093/oxfordjournals.jbchem.a002918;
RA   Karaya K., Shimizu T., Taketo A.;
RT   "New gene cluster for lantibiotic streptin possibly involved in
RT   streptolysin S formation.";
RL   J. Biochem. 129:769-775(2001).
CC   -!- FUNCTION: Implicated in the export process of the lantibiotic SrtA.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; AB030831; BAB08166.1; -; Genomic_DNA.
DR   RefSeq; WP_010922274.1; NZ_WXZK01000013.1.
DR   AlphaFoldDB; P0C0E2; -.
DR   SMR; P0C0E2; -.
DR   eggNOG; COG1131; Bacteria.
DR   OMA; ICGKTKA; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR   GO; GO:0043213; P:bacteriocin transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR022501; ABC_Gallidermin_ATP-bd.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR03740; galliderm_ABC; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Bacteriocin transport; Nucleotide-binding; Protein transport;
KW   Transport.
FT   CHAIN           1..229
FT                   /note="Lantibiotic transport ATP-binding protein SrtF"
FT                   /id="PRO_0000092978"
FT   DOMAIN          2..225
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         34..41
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   229 AA;  25679 MW;  065ED5C34ACA8D07 CRC64;
     MLKIQNLKKS YGKRTILNNV NMNIPKGKVY ALIGPNGAGK STIMKILTGL VSKTSGSIIF
     EGREWSRRDL RKIGSIIEEP PLYKNLSAYD NMKVVTTMLG VSESTILPLL NKVGLGNIDK
     RPVKQFSLGM KQRLGIAISL INSPKLLILD EPTNGLDPIG IQELREIIES FKSEGMTIMI
     SSHILSEVEH LADFIGFIYE GKIILEKEYD GSENLEELFN NQILFEKRR