ID   SRTM1_MOUSE             Reviewed;         107 AA.
AC   Q8CD78;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Serine-rich and transmembrane domain-containing protein 1;
GN   Name=Sertm1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AK031306; BAC27339.1; -; mRNA.
DR   EMBL; BC058995; AAH58995.1; -; mRNA.
DR   CCDS; CCDS17355.1; -.
DR   RefSeq; NP_808522.1; NM_177854.4.
DR   AlphaFoldDB; Q8CD78; -.
DR   SMR; Q8CD78; -.
DR   STRING; 10090.ENSMUSP00000064870; -.
DR   iPTMnet; Q8CD78; -.
DR   PhosphoSitePlus; Q8CD78; -.
DR   PaxDb; Q8CD78; -.
DR   PRIDE; Q8CD78; -.
DR   Antibodypedia; 57544; 9 antibodies from 5 providers.
DR   DNASU; 329641; -.
DR   Ensembl; ENSMUST00000070342; ENSMUSP00000064870; ENSMUSG00000056306.
DR   Ensembl; ENSMUST00000162201; ENSMUSP00000124102; ENSMUSG00000056306.
DR   GeneID; 329641; -.
DR   KEGG; mmu:329641; -.
DR   UCSC; uc008pfx.2; mouse.
DR   CTD; 400120; -.
DR   MGI; MGI:3607715; Sertm1.
DR   VEuPathDB; HostDB:ENSMUSG00000056306; -.
DR   eggNOG; ENOG502S4A5; Eukaryota.
DR   GeneTree; ENSGT00390000016881; -.
DR   HOGENOM; CLU_2196038_0_0_1; -.
DR   InParanoid; Q8CD78; -.
DR   OMA; PGGRQGN; -.
DR   PhylomeDB; Q8CD78; -.
DR   TreeFam; TF338260; -.
DR   BioGRID-ORCS; 329641; 2 hits in 71 CRISPR screens.
DR   PRO; PR:Q8CD78; -.
DR   Proteomes; UP000000589; Chromosome 3.
DR   RNAct; Q8CD78; protein.
DR   Bgee; ENSMUSG00000056306; Expressed in subiculum and 75 other tissues.
DR   Genevisible; Q8CD78; MM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; ISO:MGI.
DR   InterPro; IPR031741; SERTM.
DR   PANTHER; PTHR35660; PTHR35660; 1.
DR   Pfam; PF15872; SRTM1; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..107
FT                   /note="Serine-rich and transmembrane domain-containing
FT                   protein 1"
FT                   /id="PRO_0000331522"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   107 AA;  11392 MW;  DF57D136EF7137A1 CRC64;
     MSEADSSSGF AGSVENGTFL ELFPTSLSTS VDSSSGHLSN VYIYVSIFLS LLAFLLLLLI
     IALQRLKNII SSSSSYPEYP SDAGSSFTNL EVCSISSQRS TFSNLSS