ABHDD_DANRE
ID ABHDD_DANRE Reviewed; 337 AA.
AC Q32LS6;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Protein ABHD13 {ECO:0000305};
DE EC=3.-.-.-;
DE AltName: Full=Alpha/beta hydrolase domain-containing protein 13 {ECO:0000305};
DE Short=Abhydrolase domain-containing protein 13 {ECO:0000250|UniProtKB:Q7L211};
GN Name=abhd13 {ECO:0000250|UniProtKB:Q7L211}; ORFNames=zgc:123286;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=AB; TISSUE=Intestine;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the serine esterase family. {ECO:0000305}.
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DR EMBL; BC109445; AAI09446.1; -; mRNA.
DR RefSeq; NP_001032774.1; NM_001037685.1.
DR AlphaFoldDB; Q32LS6; -.
DR SMR; Q32LS6; -.
DR STRING; 7955.ENSDARP00000076697; -.
DR ESTHER; danre-q32ls6; ABHD13-BEM46.
DR PaxDb; Q32LS6; -.
DR Ensembl; ENSDART00000082260; ENSDARP00000076697; ENSDARG00000059209.
DR GeneID; 561333; -.
DR KEGG; dre:561333; -.
DR CTD; 84945; -.
DR ZFIN; ZDB-GENE-051120-54; abhd13.
DR eggNOG; KOG4391; Eukaryota.
DR GeneTree; ENSGT00940000158114; -.
DR HOGENOM; CLU_029375_2_0_1; -.
DR InParanoid; Q32LS6; -.
DR OMA; PNGGHND; -.
DR OrthoDB; 1036130at2759; -.
DR PhylomeDB; Q32LS6; -.
DR TreeFam; TF315122; -.
DR PRO; PR:Q32LS6; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 9.
DR Bgee; ENSDARG00000059209; Expressed in mature ovarian follicle and 19 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; -; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR022742; Hydrolase_4.
DR Pfam; PF12146; Hydrolase_4; 1.
DR PRINTS; PR00111; ABHYDROLASE.
DR SUPFAM; SSF53474; SSF53474; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Membrane; Reference proteome; Signal-anchor;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..337
FT /note="Protein ABHD13"
FT /id="PRO_0000281079"
FT TRANSMEM 30..50
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT ACT_SITE 193
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT ACT_SITE 268
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT ACT_SITE 298
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT CARBOHYD 299
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 337 AA; 37901 MW; DCEC6F72F958D7F0 CRC64;
MEKPWRLWGP LEACLLSVCA WSWGFCRVSL LALILTFHLY GGFVLLGLIL ASLAGILYKF
QDVLLYFPDQ PSSSRLYVPM PTGIPHENVY IRTKDGIRLN LILLRYTGEN PAGAPTILYF
HGNAGNIGHR VPNALLMLVN LKANVVLVDY RGYGKSEGDP SEDGLYQDAE ATLDYVMTRP
DIDKTKVVLF GRSLGGAVAI RLASCNPHRV AAIMVENTFL SIPHMAATLF SFFPMRYLPL
WCYKNKFLSY RHVVPCRMPS LFISGLSDQL IPPVMMKQLY ELSPSRTKRL AIFPEGTHND
TWQCQGYFSA LEQFMKELLK SHAREETTQG TASVTII