ID   SRX1C_SARPE             Reviewed;          39 AA.
AC   P08377;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Sarcotoxin-1C;
DE   AltName: Full=Sarcotoxin IC;
OS   Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC   Sarcophagidae; Sarcophaga; Boettcherisca.
OX   NCBI_TaxID=7386;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT ARG-39.
RX   PubMed=3888997; DOI=10.1016/s0021-9258(17)39590-x;
RA   Okada M., Natori S.;
RT   "Primary structure of sarcotoxin I, an antibacterial protein induced in the
RT   hemolymph of Sarcophaga peregrina (flesh fly) larvae.";
RL   J. Biol. Chem. 260:7174-7177(1985).
CC   -!- FUNCTION: Sarcotoxins, which are potent bactericidal proteins, are
CC       produced in response to injury. They are cytotoxic to both Gram-
CC       positive and Gram-negative bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the cecropin family. {ECO:0000305}.
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DR   PIR; C22625; CKFHCS.
DR   AlphaFoldDB; P08377; -.
DR   SMR; P08377; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019731; P:antibacterial humoral response; IEA:InterPro.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:UniProt.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   InterPro; IPR000875; Cecropin.
DR   InterPro; IPR020400; Cecropin_insect.
DR   PANTHER; PTHR38329; PTHR38329; 1.
DR   Pfam; PF00272; Cecropin; 1.
DR   PROSITE; PS00268; CECROPIN; 1.
PE   1: Evidence at protein level;
KW   Amidation; Antibiotic; Antimicrobial; Direct protein sequencing; Immunity;
KW   Innate immunity; Secreted.
FT   PEPTIDE         1..39
FT                   /note="Sarcotoxin-1C"
FT                   /id="PRO_0000044685"
FT   MOD_RES         39
FT                   /note="Arginine amide"
FT                   /evidence="ECO:0000269|PubMed:3888997"
SQ   SEQUENCE   39 AA;  4227 MW;  11E79F4F405E855A CRC64;
     GWLRKIGKKI ERVGQHTRDA TIQVLGIAQQ AANVAATAR