ID   SSAA1_STAAC             Reviewed;         255 AA.
AC   Q5HCY4;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Staphylococcal secretory antigen ssaA1;
DE   Flags: Precursor;
GN   Name=ssaA1; OrderedLocusNames=SACOL2581;
OS   Staphylococcus aureus (strain COL).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COL;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- FUNCTION: Not known; immunogenic protein. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   EMBL; CP000046; AAW38583.1; -; Genomic_DNA.
DR   RefSeq; WP_000725225.1; NC_002951.2.
DR   AlphaFoldDB; Q5HCY4; -.
DR   SMR; Q5HCY4; -.
DR   EnsemblBacteria; AAW38583; AAW38583; SACOL2581.
DR   KEGG; sac:SACOL2581; -.
DR   HOGENOM; CLU_016043_11_0_9; -.
DR   OMA; NTWGNAN; -.
DR   Proteomes; UP000000530; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007921; CHAP_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS50911; CHAP; 1.
PE   3: Inferred from homology;
KW   Repeat; Secreted; Signal; Virulence.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..255
FT                   /note="Staphylococcal secretory antigen ssaA1"
FT                   /id="PRO_0000045308"
FT   REPEAT          75..78
FT                   /note="1"
FT   REPEAT          88..91
FT                   /note="2"
FT   REPEAT          98..101
FT                   /note="3"
FT   DOMAIN          134..255
FT                   /note="Peptidase C51"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00048"
FT   REGION          75..101
FT                   /note="3 X 4 AA repeats of Y-N-N-Y"
SQ   SEQUENCE   255 AA;  27589 MW;  B433F2B5FD149970 CRC64;
     MKKIVTATIA TAGLATIAFA GHDAQAAEQN NNGYNSNDAQ SYSYTYTIDA QGNYHYTWTG
     NWNPSQLTQN NTYYYNNYNT YSYNNASYNN YYNHSYQYNN YTNNSQTATN NYYTGGSGAS
     YSTTSNNVHV TTTAAPSSNG RSISNGYASG SNLYTSGQCT YYVFDRVGGK IGSTWGNASN
     WANAAASSGY TVNNTPKVGA IMQTTQGYYG HVAYVEGVNS NGSVRVSEMN YGHGAGVVTS
     RTISANQAGS YNFIH