SSAA1_STAAM
ID SSAA1_STAAM Reviewed; 255 AA.
AC Q7A2K8;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Staphylococcal secretory antigen ssaA1;
DE Flags: Precursor;
GN Name=ssaA1; OrderedLocusNames=SAV2566;
OS Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=158878;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mu50 / ATCC 700699;
RX PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA Hiramatsu K.;
RT "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL Lancet 357:1225-1240(2001).
CC -!- FUNCTION: Not known; immunogenic protein. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR EMBL; BA000017; BAB58728.1; -; Genomic_DNA.
DR RefSeq; WP_000725225.1; NC_002758.2.
DR AlphaFoldDB; Q7A2K8; -.
DR SMR; Q7A2K8; -.
DR PaxDb; Q7A2K8; -.
DR EnsemblBacteria; BAB58728; BAB58728; SAV2566.
DR KEGG; sav:SAV2566; -.
DR HOGENOM; CLU_016043_11_0_9; -.
DR OMA; NTWGNAN; -.
DR BioCyc; SAUR158878:SAV_RS13995-MON; -.
DR Proteomes; UP000002481; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR007921; CHAP_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR SUPFAM; SSF54001; SSF54001; 1.
DR PROSITE; PS50911; CHAP; 1.
PE 3: Inferred from homology;
KW Repeat; Secreted; Signal; Virulence.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..255
FT /note="Staphylococcal secretory antigen ssaA1"
FT /id="PRO_0000045309"
FT REPEAT 75..78
FT /note="1"
FT REPEAT 88..91
FT /note="2"
FT REPEAT 98..101
FT /note="3"
FT DOMAIN 134..255
FT /note="Peptidase C51"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00048"
FT REGION 75..101
FT /note="3 X 4 AA repeats of Y-N-N-Y"
SQ SEQUENCE 255 AA; 27589 MW; B433F2B5FD149970 CRC64;
MKKIVTATIA TAGLATIAFA GHDAQAAEQN NNGYNSNDAQ SYSYTYTIDA QGNYHYTWTG
NWNPSQLTQN NTYYYNNYNT YSYNNASYNN YYNHSYQYNN YTNNSQTATN NYYTGGSGAS
YSTTSNNVHV TTTAAPSSNG RSISNGYASG SNLYTSGQCT YYVFDRVGGK IGSTWGNASN
WANAAASSGY TVNNTPKVGA IMQTTQGYYG HVAYVEGVNS NGSVRVSEMN YGHGAGVVTS
RTISANQAGS YNFIH