ID   SSAA2_STAAC             Reviewed;         267 AA.
AC   Q5HDQ9;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Staphylococcal secretory antigen ssaA2;
DE   Flags: Precursor;
GN   Name=ssaA2; OrderedLocusNames=SACOL2291;
OS   Staphylococcus aureus (strain COL).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COL;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- FUNCTION: Not known; immunogenic protein. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   EMBL; CP000046; AAW38511.1; -; Genomic_DNA.
DR   RefSeq; WP_000717381.1; NC_002951.2.
DR   AlphaFoldDB; Q5HDQ9; -.
DR   SMR; Q5HDQ9; -.
DR   EnsemblBacteria; AAW38511; AAW38511; SACOL2291.
DR   KEGG; sac:SACOL2291; -.
DR   HOGENOM; CLU_016043_11_0_9; -.
DR   OMA; WSPERFN; -.
DR   Proteomes; UP000000530; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007921; CHAP_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   Pfam; PF05257; CHAP; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS50911; CHAP; 1.
PE   3: Inferred from homology;
KW   Repeat; Secreted; Signal; Virulence.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..267
FT                   /note="Staphylococcal secretory antigen ssaA2"
FT                   /id="PRO_0000045314"
FT   REPEAT          83..85
FT                   /note="1"
FT   REPEAT          86..88
FT                   /note="2"
FT   REPEAT          89..91
FT                   /note="3"
FT   REPEAT          95..97
FT                   /note="4"
FT   REPEAT          101..103
FT                   /note="5"
FT   REPEAT          104..106
FT                   /note="6"
FT   REPEAT          113..115
FT                   /note="7"
FT   DOMAIN          146..267
FT                   /note="Peptidase C51"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00048"
FT   REGION          83..115
FT                   /note="7 X 3 AA repeats of Y-[NS]-N"
SQ   SEQUENCE   267 AA;  29327 MW;  F0F72FEE2A32897A CRC64;
     MKKIATATIA TAGFATIAIA SGNQAHASEQ DNYGYNPNDP TSYSYTYTID AQGNYHYTWK
     GNWHPSQLNQ DNGYYSYYYY NGYNNYNNYN NGYSYNNYSR YNNYSNNNQS YNYNNYNSYN
     TNSYRTGGLG ASYSTSSNNV QVTTTMAPSS NGRSISSGYT SGRNLYTSGQ CTYYVFDRVG
     GKIGSTWGNA SNWANAAARA GYTVNNTPKA GAIMQTTQGA YGHVAYVESV NSNGSVRVSE
     MNYGYGPGVV TSRTISASQA AGYNFIH