ID   SSAA2_STAAN             Reviewed;         267 AA.
AC   Q7A423;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Staphylococcal secretory antigen ssaA2;
DE   Flags: Precursor;
GN   Name=ssaA2; OrderedLocusNames=SA2093;
OS   Staphylococcus aureus (strain N315).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N315;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=N315;
RA   Vaezzadeh A.R., Deshusses J., Lescuyer P., Hochstrasser D.F.;
RT   "Shotgun proteomic analysis of total and membrane protein extracts of S.
RT   aureus strain N315.";
RL   Submitted (OCT-2007) to UniProtKB.
CC   -!- FUNCTION: Not known; immunogenic protein. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   EMBL; BA000018; BAB43391.1; -; Genomic_DNA.
DR   PIR; F90028; F90028.
DR   RefSeq; WP_000717381.1; NC_002745.2.
DR   AlphaFoldDB; Q7A423; -.
DR   SMR; Q7A423; -.
DR   EnsemblBacteria; BAB43391; BAB43391; BAB43391.
DR   KEGG; sau:SA2093; -.
DR   HOGENOM; CLU_016043_11_0_9; -.
DR   OMA; WSPERFN; -.
DR   Proteomes; UP000000751; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007921; CHAP_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   Pfam; PF05257; CHAP; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS50911; CHAP; 1.
PE   1: Evidence at protein level;
KW   Repeat; Secreted; Signal; Virulence.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..267
FT                   /note="Staphylococcal secretory antigen ssaA2"
FT                   /id="PRO_0000045316"
FT   REPEAT          83..85
FT                   /note="1"
FT   REPEAT          86..88
FT                   /note="2"
FT   REPEAT          89..91
FT                   /note="3"
FT   REPEAT          95..97
FT                   /note="4"
FT   REPEAT          101..103
FT                   /note="5"
FT   REPEAT          104..106
FT                   /note="6"
FT   REPEAT          113..115
FT                   /note="7"
FT   DOMAIN          146..267
FT                   /note="Peptidase C51"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00048"
FT   REGION          83..115
FT                   /note="7 X 3 AA repeats of Y-[NS]-N"
SQ   SEQUENCE   267 AA;  29327 MW;  F0F72FEE2A32897A CRC64;
     MKKIATATIA TAGFATIAIA SGNQAHASEQ DNYGYNPNDP TSYSYTYTID AQGNYHYTWK
     GNWHPSQLNQ DNGYYSYYYY NGYNNYNNYN NGYSYNNYSR YNNYSNNNQS YNYNNYNSYN
     TNSYRTGGLG ASYSTSSNNV QVTTTMAPSS NGRSISSGYT SGRNLYTSGQ CTYYVFDRVG
     GKIGSTWGNA SNWANAAARA GYTVNNTPKA GAIMQTTQGA YGHVAYVESV NSNGSVRVSE
     MNYGYGPGVV TSRTISASQA AGYNFIH