ID   SSAA2_STAAW             Reviewed;         269 AA.
AC   Q8NV83;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Staphylococcal secretory antigen ssaA2;
DE   Flags: Precursor;
GN   Name=ssaA2; OrderedLocusNames=MW2217;
OS   Staphylococcus aureus (strain MW2).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=196620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MW2;
RX   PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA   Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA   Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT   "Genome and virulence determinants of high virulence community-acquired
RT   MRSA.";
RL   Lancet 359:1819-1827(2002).
CC   -!- FUNCTION: Not known; immunogenic protein. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   EMBL; BA000033; BAB96082.1; -; Genomic_DNA.
DR   RefSeq; WP_000717388.1; NC_003923.1.
DR   AlphaFoldDB; Q8NV83; -.
DR   SMR; Q8NV83; -.
DR   EnsemblBacteria; BAB96082; BAB96082; BAB96082.
DR   KEGG; sam:MW2217; -.
DR   HOGENOM; CLU_016043_11_0_9; -.
DR   OMA; WSPERFN; -.
DR   Proteomes; UP000000418; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007921; CHAP_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   Pfam; PF05257; CHAP; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS50911; CHAP; 1.
PE   3: Inferred from homology;
KW   Repeat; Secreted; Signal; Virulence.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..269
FT                   /note="Staphylococcal secretory antigen ssaA2"
FT                   /id="PRO_0000045319"
FT   REPEAT          83..85
FT                   /note="1"
FT   REPEAT          86..88
FT                   /note="2"
FT   REPEAT          89..91
FT                   /note="3"
FT   REPEAT          95..97
FT                   /note="4"
FT   REPEAT          101..103
FT                   /note="5"
FT   REPEAT          104..106
FT                   /note="6"
FT   REPEAT          113..115
FT                   /note="7"
FT   DOMAIN          148..269
FT                   /note="Peptidase C51"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00048"
FT   REGION          83..115
FT                   /note="7 X 3 AA repeats of Y-[NS]-N"
SQ   SEQUENCE   269 AA;  29604 MW;  36E341415CA5F2FD CRC64;
     MKKIATATIA TAGFATIAIA SGNQAHASEQ DNYGYNPNDP TSYSYTYTID AQGNYHYTWK
     GNWHPSQLNQ DNGYYSYYYY NGYNNYNYNN YNNGYSYNNY SRYNNYSNNN QSYNYNNYNS
     YNTNSYRTGG LGASYSTSSN NVQVTTTMAP SSNGRSISSG YTSGRNLYTS GQCTYYVFDR
     VGGKIGSTWG NASNWANAAA RAGYTVNNTP KAGAIMQTTQ GAYGHVAYVE SVNSNGSVRV
     SEMNYGYGPG VVTSRTISAS QAAGYNFIH