ID   SSAA_STAEP              Reviewed;         257 AA.
AC   Q9KJT6;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Staphylococcal secretory antigen SsaA;
DE   Flags: Precursor;
GN   Name=ssaA;
OS   Staphylococcus epidermidis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1282;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=ATCC 14990 / DSM 20044 / CIP 81.55 / NCTC 11047;
RX   PubMed=11064268; DOI=10.1111/j.1574-695x.2000.tb01525.x;
RA   Lang S., Livesley M.A., Lambert P.A., Littler W.A., Elliott T.S.;
RT   "Identification of a novel antigen from Staphylococcus epidermidis.";
RL   FEMS Immunol. Med. Microbiol. 29:213-220(2000).
CC   -!- FUNCTION: Not known; immunogenic protein expressed during sepsis and
CC       particularly during episodes of infective endocarditis.
CC       {ECO:0000269|PubMed:11064268}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
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DR   EMBL; AF162275; AAF80452.1; -; Genomic_DNA.
DR   RefSeq; WP_002440903.1; NZ_WLVA01000001.1.
DR   AlphaFoldDB; Q9KJT6; -.
DR   SMR; Q9KJT6; -.
DR   GeneID; 50018027; -.
DR   PATRIC; fig|1282.1161.peg.979; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007921; CHAP_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   Pfam; PF05257; CHAP; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS50911; CHAP; 1.
PE   3: Inferred from homology;
KW   Repeat; Secreted; Signal; Virulence.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..257
FT                   /note="Staphylococcal secretory antigen SsaA"
FT                   /id="PRO_0000045320"
FT   REPEAT          73..75
FT                   /note="1"
FT   REPEAT          76..78
FT                   /note="2"
FT   REPEAT          84..86
FT                   /note="3"
FT   REPEAT          87..89
FT                   /note="4"
FT   REPEAT          90..92
FT                   /note="5"
FT   REPEAT          93..95
FT                   /note="6"
FT   REPEAT          96..98
FT                   /note="7"
FT   REPEAT          99..101
FT                   /note="8"
FT   DOMAIN          136..257
FT                   /note="Peptidase C51"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00048"
FT   REGION          73..101
FT                   /note="8 X 3 AA repeats of Y-[NS]-N"
FT   REGION          101..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   257 AA;  27912 MW;  A242B6BE0B92BA0A CRC64;
     MKKIATATIA TAGIATFAFA HHDAQAAEQN NDGYNPNDPY SYSYTYTIDA EGNYHYTWKG
     NWSPDRVNTS YNYNNYNNYN YYGYNNYSNY NNYSNYNNYN NYQSNNTQSQ RTTQPTGGLG
     ASYSTSSSNV HVTTTSAPSS NGVSLSNARS ASGNLYTSGQ CTYYVFDRVG GKIGSTWGNA
     NNWANAAARS GYTVNNSPAK GAILQTSQGA YGHVAYVEGV NSNGSIRVSE MNYGHGAGVV
     TSRTISASQA ASYNYIH