ID   SSAA_STAEQ              Reviewed;         257 AA.
AC   Q5HLV2;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Staphylococcal secretory antigen SsaA;
DE   Flags: Precursor;
GN   Name=ssaA1; OrderedLocusNames=SERP1880;
GN   and
GN   Name=ssaA2; OrderedLocusNames=SERP2136;
OS   Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35984 / RP62A;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- FUNCTION: Not known; immunogenic protein. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   EMBL; CP000029; AAW55260.1; -; Genomic_DNA.
DR   EMBL; CP000029; AAW53036.1; -; Genomic_DNA.
DR   RefSeq; WP_002440903.1; NC_002976.3.
DR   AlphaFoldDB; Q5HLV2; -.
DR   SMR; Q5HLV2; -.
DR   STRING; 176279.SERP1880; -.
DR   EnsemblBacteria; AAW53036; AAW53036; SERP2136.
DR   EnsemblBacteria; AAW55260; AAW55260; SERP1880.
DR   GeneID; 50018027; -.
DR   KEGG; ser:SERP1880; -.
DR   KEGG; ser:SERP2136; -.
DR   eggNOG; COG3942; Bacteria.
DR   HOGENOM; CLU_016043_11_0_9; -.
DR   OMA; WSPERFN; -.
DR   OrthoDB; 682655at2; -.
DR   Proteomes; UP000000531; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007921; CHAP_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   Pfam; PF05257; CHAP; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS50911; CHAP; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; Secreted; Signal; Virulence.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..257
FT                   /note="Staphylococcal secretory antigen SsaA"
FT                   /id="PRO_0000045321"
FT   REPEAT          73..75
FT                   /note="1"
FT   REPEAT          76..78
FT                   /note="2"
FT   REPEAT          84..86
FT                   /note="3"
FT   REPEAT          87..89
FT                   /note="4"
FT   REPEAT          90..92
FT                   /note="5"
FT   REPEAT          93..95
FT                   /note="6"
FT   REPEAT          96..98
FT                   /note="7"
FT   REPEAT          99..101
FT                   /note="8"
FT   DOMAIN          136..257
FT                   /note="Peptidase C51"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00048"
FT   REGION          73..101
FT                   /note="8 X 3 AA tandem repeats of Y-[NS]-N"
FT   REGION          101..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   257 AA;  27912 MW;  A242B6BE0B92BA0A CRC64;
     MKKIATATIA TAGIATFAFA HHDAQAAEQN NDGYNPNDPY SYSYTYTIDA EGNYHYTWKG
     NWSPDRVNTS YNYNNYNNYN YYGYNNYSNY NNYSNYNNYN NYQSNNTQSQ RTTQPTGGLG
     ASYSTSSSNV HVTTTSAPSS NGVSLSNARS ASGNLYTSGQ CTYYVFDRVG GKIGSTWGNA
     NNWANAAARS GYTVNNSPAK GAILQTSQGA YGHVAYVEGV NSNGSIRVSE MNYGHGAGVV
     TSRTISASQA ASYNYIH