ID   SSAA_STAES              Reviewed;         257 AA.
AC   Q7CCJ3;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Staphylococcal secretory antigen SsaA;
DE   Flags: Precursor;
GN   Name=ssaA; OrderedLocusNames=SE_1872;
GN   and
GN   Name=ssaA2; OrderedLocusNames=SE_2124;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- FUNCTION: Not known; immunogenic protein. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   EMBL; AE015929; AAO05766.1; -; Genomic_DNA.
DR   EMBL; AE015929; AAO05513.1; -; Genomic_DNA.
DR   RefSeq; NP_765427.1; NC_004461.1.
DR   RefSeq; NP_765679.1; NC_004461.1.
DR   RefSeq; WP_002440903.1; NZ_WBME01000013.1.
DR   AlphaFoldDB; Q7CCJ3; -.
DR   SMR; Q7CCJ3; -.
DR   STRING; 176280.SE_1872; -.
DR   EnsemblBacteria; AAO05513; AAO05513; SE_1872.
DR   EnsemblBacteria; AAO05766; AAO05766; SE_2124.
DR   GeneID; 50018027; -.
DR   KEGG; sep:SE_1872; -.
DR   KEGG; sep:SE_2124; -.
DR   PATRIC; fig|176280.10.peg.1829; -.
DR   eggNOG; COG3942; Bacteria.
DR   HOGENOM; CLU_016043_11_0_9; -.
DR   OMA; WSPERFN; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007921; CHAP_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   Pfam; PF05257; CHAP; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS50911; CHAP; 1.
PE   3: Inferred from homology;
KW   Repeat; Secreted; Signal; Virulence.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..257
FT                   /note="Staphylococcal secretory antigen SsaA"
FT                   /id="PRO_0000045322"
FT   REPEAT          73..75
FT                   /note="1"
FT   REPEAT          76..78
FT                   /note="2"
FT   REPEAT          84..86
FT                   /note="3"
FT   REPEAT          87..89
FT                   /note="4"
FT   REPEAT          90..92
FT                   /note="5"
FT   REPEAT          93..95
FT                   /note="6"
FT   REPEAT          96..98
FT                   /note="7"
FT   REPEAT          99..101
FT                   /note="8"
FT   DOMAIN          136..257
FT                   /note="Peptidase C51"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00048"
FT   REGION          73..101
FT                   /note="8 X 3 AA tandem repeats of Y-[NS]-N"
FT   REGION          101..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   257 AA;  27912 MW;  A242B6BE0B92BA0A CRC64;
     MKKIATATIA TAGIATFAFA HHDAQAAEQN NDGYNPNDPY SYSYTYTIDA EGNYHYTWKG
     NWSPDRVNTS YNYNNYNNYN YYGYNNYSNY NNYSNYNNYN NYQSNNTQSQ RTTQPTGGLG
     ASYSTSSSNV HVTTTSAPSS NGVSLSNARS ASGNLYTSGQ CTYYVFDRVG GKIGSTWGNA
     NNWANAAARS GYTVNNSPAK GAILQTSQGA YGHVAYVEGV NSNGSIRVSE MNYGHGAGVV
     TSRTISASQA ASYNYIH