SSB2_STRCO
ID SSB2_STRCO Reviewed; 199 AA.
AC Q9X8U3;
DT 24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 119.
DE RecName: Full=Single-stranded DNA-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_00984};
DE Short=SSB 2 {ECO:0000255|HAMAP-Rule:MF_00984};
GN Name=ssb2; OrderedLocusNames=SCO3907; ORFNames=SCH24.29;
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145;
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
RN [2]
RP PHOSPHORYLATION.
RX PubMed=16549871; DOI=10.1093/nar/gkj514;
RA Mijakovic I., Petranovic D., Macek B., Cepo T., Mann M., Davies J.,
RA Jensen P.R., Vujaklija D.;
RT "Bacterial single-stranded DNA-binding proteins are phosphorylated on
RT tyrosine.";
RL Nucleic Acids Res. 34:1588-1596(2006).
CC -!- SUBUNIT: Homotetramer. {ECO:0000255|HAMAP-Rule:MF_00984}.
CC -!- PTM: Phosphorylated on tyrosine residue(s) when expressed in E.coli.
CC {ECO:0000269|PubMed:16549871}.
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DR EMBL; AL939118; CAB42735.1; -; Genomic_DNA.
DR PIR; T36594; T36594.
DR RefSeq; NP_628093.1; NC_003888.3.
DR RefSeq; WP_011029303.1; NZ_VNID01000003.1.
DR PDB; 3EIV; X-ray; 2.14 A; A/B/C/D=1-199.
DR PDBsum; 3EIV; -.
DR AlphaFoldDB; Q9X8U3; -.
DR SMR; Q9X8U3; -.
DR STRING; 100226.SCO3907; -.
DR GeneID; 1099343; -.
DR KEGG; sco:SCO3907; -.
DR PATRIC; fig|100226.15.peg.3981; -.
DR eggNOG; COG0629; Bacteria.
DR HOGENOM; CLU_078758_1_0_11; -.
DR InParanoid; Q9X8U3; -.
DR OMA; GQMQERT; -.
DR PhylomeDB; Q9X8U3; -.
DR EvolutionaryTrace; Q9X8U3; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0009295; C:nucleoid; IBA:GO_Central.
DR GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0051096; P:positive regulation of helicase activity; IBA:GO_Central.
DR CDD; cd04496; SSB_OBF; 1.
DR DisProt; DP00854; -.
DR Gene3D; 2.40.50.140; -; 1.
DR HAMAP; MF_00984; SSB; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR000424; Primosome_PriB/ssb.
DR InterPro; IPR011344; ssDNA-bd.
DR PANTHER; PTHR10302; PTHR10302; 1.
DR Pfam; PF00436; SSB; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR TIGRFAMs; TIGR00621; ssb; 1.
DR PROSITE; PS50935; SSB; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Phosphoprotein; Reference proteome.
FT CHAIN 1..199
FT /note="Single-stranded DNA-binding protein 2"
FT /id="PRO_0000096116"
FT DOMAIN 1..110
FT /note="SSB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00984"
FT REGION 114..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 6..15
FT /evidence="ECO:0007829|PDB:3EIV"
FT STRAND 18..21
FT /evidence="ECO:0007829|PDB:3EIV"
FT STRAND 27..35
FT /evidence="ECO:0007829|PDB:3EIV"
FT TURN 42..45
FT /evidence="ECO:0007829|PDB:3EIV"
FT STRAND 46..48
FT /evidence="ECO:0007829|PDB:3EIV"
FT STRAND 53..60
FT /evidence="ECO:0007829|PDB:3EIV"
FT HELIX 62..70
FT /evidence="ECO:0007829|PDB:3EIV"
FT STRAND 76..86
FT /evidence="ECO:0007829|PDB:3EIV"
FT STRAND 98..109
FT /evidence="ECO:0007829|PDB:3EIV"
FT STRAND 111..119
FT /evidence="ECO:0007829|PDB:3EIV"
SQ SEQUENCE 199 AA; 19907 MW; CB291962A445AA5F CRC64;
MAGETVITVV GNLVDDPELR FTPSGAAVAK FRVASTPRTF DRQTNEWKDG ESLFLTCSVW
RQAAENVAES LQRGMRVIVQ GRLKQRSYED REGVKRTVYE LDVDEVGASL RSATAKVTKT
SGQGRGGQGG YGGGGGGQGG GGWGGGPGGG QQGGGAPADD PWATGGAPAG GQQGGGGQGG
GGWGGGSGGG GGYSDEPPF