ID   SSB_AQUAE               Reviewed;         147 AA.
AC   O66475;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Single-stranded DNA-binding protein {ECO:0000255|HAMAP-Rule:MF_00984};
DE            Short=SSB {ECO:0000255|HAMAP-Rule:MF_00984};
GN   Name=ssb; OrderedLocusNames=aq_064;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Plays an important role in DNA replication, recombination and
CC       repair. Binds to ssDNA and to an array of partner proteins to recruit
CC       them to their sites of action during DNA metabolism.
CC       {ECO:0000255|HAMAP-Rule:MF_00984}.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000255|HAMAP-Rule:MF_00984}.
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DR   EMBL; AE000657; AAC06439.1; -; Genomic_DNA.
DR   PIR; H70305; H70305.
DR   RefSeq; NP_213035.1; NC_000918.1.
DR   RefSeq; WP_010879973.1; NC_000918.1.
DR   AlphaFoldDB; O66475; -.
DR   SMR; O66475; -.
DR   STRING; 224324.aq_064; -.
DR   EnsemblBacteria; AAC06439; AAC06439; aq_064.
DR   KEGG; aae:aq_064; -.
DR   eggNOG; COG0629; Bacteria.
DR   HOGENOM; CLU_078758_6_0_0; -.
DR   InParanoid; O66475; -.
DR   OMA; RFRDSNH; -.
DR   OrthoDB; 1942216at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd04496; SSB_OBF; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00984; SSB; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR000424; Primosome_PriB/ssb.
DR   InterPro; IPR011344; ssDNA-bd.
DR   PANTHER; PTHR10302; PTHR10302; 1.
DR   Pfam; PF00436; SSB; 1.
DR   PIRSF; PIRSF002070; SSB; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00621; ssb; 1.
DR   PROSITE; PS50935; SSB; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA recombination; DNA repair; DNA replication; DNA-binding;
KW   Reference proteome.
FT   CHAIN           1..147
FT                   /note="Single-stranded DNA-binding protein"
FT                   /id="PRO_0000095999"
FT   DOMAIN          1..105
FT                   /note="SSB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00984"
FT   REGION          108..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           142..147
FT                   /note="Important for interaction with partner proteins"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00984"
SQ   SEQUENCE   147 AA;  17132 MW;  BBBACA5B282E9B51 CRC64;
     MLNKVFIIGR LTGDPVITYL PSGTPVVEFT LAYNRRYKNQ NGEFQEESHF FDVKAYGKMA
     EDWATRFSKG YLVLVEGRLS QEKWEKEGKK FSKVRIIAEN VRLINRPKGA ELQAEEEEEV
     PPIEEEIEKL GKEEEKPFTD EEDEIPF