ID   SSB_SERMA               Reviewed;         176 AA.
AC   P25762;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=Single-stranded DNA-binding protein {ECO:0000255|HAMAP-Rule:MF_00984};
DE            Short=SSB {ECO:0000255|HAMAP-Rule:MF_00984};
GN   Name=ssb;
OS   Serratia marcescens.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Sr41;
RX   PubMed=8486286; DOI=10.1016/0378-1119(93)90614-9;
RA   de Vries J., Wackernagel W.;
RT   "Cloning and sequencing of the Serratia marcescens gene encoding a single-
RT   stranded DNA-binding protein (SSB) and its promoter region.";
RL   Gene 127:39-45(1993).
RN   [2]
RP   FUNCTION, DNA-BINDING, AND SUBUNIT.
RX   PubMed=7925378; DOI=10.1111/j.1432-1033.1994.00613.x;
RA   de Vries J., Genschel J., Urbanke C., Thole H., Wackernagel W.;
RT   "The single-stranded-DNA-binding proteins (SSB) of Proteus mirabilis and
RT   Serratia marcescens.";
RL   Eur. J. Biochem. 224:613-622(1994).
CC   -!- FUNCTION: Plays an important role in DNA replication, recombination and
CC       repair. Binds to ssDNA and to an array of partner proteins to recruit
CC       them to their sites of action during DNA metabolism (Probable).
CC       {ECO:0000305|PubMed:7925378}.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000255|HAMAP-Rule:MF_00984,
CC       ECO:0000269|PubMed:7925378}.
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DR   EMBL; X65080; CAA46208.1; -; Genomic_DNA.
DR   PIR; JN0632; JN0632.
DR   RefSeq; WP_004936793.1; NZ_WVHW01000003.1.
DR   AlphaFoldDB; P25762; -.
DR   SMR; P25762; -.
DR   STRING; 273526.SMDB11_3693; -.
DR   GeneID; 64306329; -.
DR   GeneID; 66712552; -.
DR   OrthoDB; 1942216at2; -.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd04496; SSB_OBF; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00984; SSB; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR000424; Primosome_PriB/ssb.
DR   InterPro; IPR011344; ssDNA-bd.
DR   PANTHER; PTHR10302; PTHR10302; 1.
DR   Pfam; PF00436; SSB; 1.
DR   PIRSF; PIRSF002070; SSB; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00621; ssb; 1.
DR   PROSITE; PS50935; SSB; 1.
PE   1: Evidence at protein level;
KW   DNA damage; DNA recombination; DNA repair; DNA replication; DNA-binding.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..176
FT                   /note="Single-stranded DNA-binding protein"
FT                   /id="PRO_0000096094"
FT   DOMAIN          6..111
FT                   /note="SSB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00984"
FT   DNA_BIND        55..61
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00984"
FT   REGION          113..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           171..176
FT                   /note="Important for interaction with partner proteins"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00984"
FT   COMPBIAS        130..164
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   176 AA;  18809 MW;  287BC3874BFE7E08 CRC64;
     MASRGVNKVI LVGNLGQDPE VRYMPNGGAV ANITLATSES WRDKATGEQK EKTEWHRVVL
     FGKLAEVAGE YLRKGSQVYI EGSLQTRKWQ DQSGQDRYTT EIVVNVGGTM QMLGGRQGGG
     APAGQSAGGQ GGWGQPQQPQ GGNQFSGGQQ QSRPAQNSAP ATSNEPPMDF DDDIPF