SSB_THEMA
ID SSB_THEMA Reviewed; 141 AA.
AC Q9WZ73;
DT 24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 126.
DE RecName: Full=Single-stranded DNA-binding protein {ECO:0000255|HAMAP-Rule:MF_00984};
DE Short=SSB {ECO:0000255|HAMAP-Rule:MF_00984};
GN Name=ssb; OrderedLocusNames=TM_0604;
OS Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS / MSB8).
OC Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX NCBI_TaxID=243274;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX PubMed=10360571; DOI=10.1038/20601;
RA Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA Smith H.O., Venter J.C., Fraser C.M.;
RT "Evidence for lateral gene transfer between Archaea and Bacteria from
RT genome sequence of Thermotoga maritima.";
RL Nature 399:323-329(1999).
CC -!- SUBUNIT: Homotetramer. {ECO:0000255|HAMAP-Rule:MF_00984}.
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DR EMBL; AE000512; AAD35689.1; -; Genomic_DNA.
DR PIR; H72354; H72354.
DR RefSeq; NP_228414.1; NC_000853.1.
DR RefSeq; WP_004081225.1; NZ_CP011107.1.
DR PDB; 1Z9F; X-ray; 2.30 A; A=1-141.
DR PDBsum; 1Z9F; -.
DR AlphaFoldDB; Q9WZ73; -.
DR SMR; Q9WZ73; -.
DR STRING; 243274.THEMA_01645; -.
DR EnsemblBacteria; AAD35689; AAD35689; TM_0604.
DR KEGG; tma:TM0604; -.
DR eggNOG; COG0629; Bacteria.
DR InParanoid; Q9WZ73; -.
DR OMA; SGSVKCR; -.
DR OrthoDB; 1942216at2; -.
DR EvolutionaryTrace; Q9WZ73; -.
DR Proteomes; UP000008183; Chromosome.
DR GO; GO:0009295; C:nucleoid; IBA:GO_Central.
DR GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0051096; P:positive regulation of helicase activity; IBA:GO_Central.
DR CDD; cd04496; SSB_OBF; 1.
DR DisProt; DP00996; -.
DR Gene3D; 2.40.50.140; -; 1.
DR HAMAP; MF_00984; SSB; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR000424; Primosome_PriB/ssb.
DR InterPro; IPR011344; ssDNA-bd.
DR PANTHER; PTHR10302; PTHR10302; 1.
DR Pfam; PF00436; SSB; 1.
DR PIRSF; PIRSF002070; SSB; 1.
DR SUPFAM; SSF50249; SSF50249; 1.
DR TIGRFAMs; TIGR00621; ssb; 1.
DR PROSITE; PS50935; SSB; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA-binding; Reference proteome.
FT CHAIN 1..141
FT /note="Single-stranded DNA-binding protein"
FT /id="PRO_0000096128"
FT DOMAIN 4..108
FT /note="SSB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00984"
FT REGION 110..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..141
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 7..15
FT /evidence="ECO:0007829|PDB:1Z9F"
FT STRAND 18..21
FT /evidence="ECO:0007829|PDB:1Z9F"
FT STRAND 27..36
FT /evidence="ECO:0007829|PDB:1Z9F"
FT STRAND 50..58
FT /evidence="ECO:0007829|PDB:1Z9F"
FT HELIX 59..68
FT /evidence="ECO:0007829|PDB:1Z9F"
FT STRAND 74..84
FT /evidence="ECO:0007829|PDB:1Z9F"
FT STRAND 96..106
FT /evidence="ECO:0007829|PDB:1Z9F"
SQ SEQUENCE 141 AA; 16298 MW; A96A77731553404E CRC64;
MSFFNKIILI GRLVRDPEER YTLSGTPVTT FTIAVDRVPR KNAPDDAQTT DFFRIVTFGR
LAEFARTYLT KGRLVLVEGE MRMRRWETPT GEKRVSPEVV ANVVRFMDRK PAETVSETEE
ELEIPEEDFS SDTFSEDEPP F
