ID   SSB_VIBCH               Reviewed;         177 AA.
AC   Q9KUW2; Q9ZA90;
DT   24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Single-stranded DNA-binding protein {ECO:0000255|HAMAP-Rule:MF_00984};
DE            Short=SSB {ECO:0000255|HAMAP-Rule:MF_00984};
GN   Name=ssb; OrderedLocusNames=VC_0397;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=El Tor C6706;
RX   PubMed=9973335; DOI=10.1128/jb.181.4.1110-1117.1999;
RA   Marsh J.W., Taylor R.K.;
RT   "Genetic and transcriptional analyses of the Vibrio cholerae mannose-
RT   sensitive hemagglutinin type 4 pilus gene locus.";
RL   J. Bacteriol. 181:1110-1117(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Plays an important role in DNA replication, recombination and
CC       repair. Binds to ssDNA and to an array of partner proteins to recruit
CC       them to their sites of action during DNA metabolism.
CC       {ECO:0000255|HAMAP-Rule:MF_00984}.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000255|HAMAP-Rule:MF_00984}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC72352.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AF079406; AAC72352.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE003852; AAF93570.1; -; Genomic_DNA.
DR   PIR; B82326; B82326.
DR   RefSeq; NP_230051.1; NC_002505.1.
DR   RefSeq; WP_000168289.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KUW2; -.
DR   SMR; Q9KUW2; -.
DR   STRING; 243277.VC_0397; -.
DR   DNASU; 2614994; -.
DR   EnsemblBacteria; AAF93570; AAF93570; VC_0397.
DR   GeneID; 57739136; -.
DR   KEGG; vch:VC_0397; -.
DR   PATRIC; fig|243277.26.peg.372; -.
DR   eggNOG; COG0629; Bacteria.
DR   HOGENOM; CLU_078758_0_2_6; -.
DR   OMA; GQMQERT; -.
DR   BioCyc; VCHO:VC0397-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0009295; C:nucleoid; IBA:GO_Central.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0051096; P:positive regulation of helicase activity; IBA:GO_Central.
DR   CDD; cd04496; SSB_OBF; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_00984; SSB; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR000424; Primosome_PriB/ssb.
DR   InterPro; IPR011344; ssDNA-bd.
DR   PANTHER; PTHR10302; PTHR10302; 1.
DR   Pfam; PF00436; SSB; 1.
DR   PIRSF; PIRSF002070; SSB; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00621; ssb; 1.
DR   PROSITE; PS50935; SSB; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA recombination; DNA repair; DNA replication; DNA-binding;
KW   Reference proteome.
FT   CHAIN           1..177
FT                   /note="Single-stranded DNA-binding protein"
FT                   /id="PRO_0000096136"
FT   DOMAIN          6..111
FT                   /note="SSB"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00984"
FT   REGION          118..177
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           172..177
FT                   /note="Important for interaction with partner proteins"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00984"
FT   COMPBIAS        130..165
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   177 AA;  19673 MW;  CD31400B29B012F9 CRC64;
     MASRGVNKVI LIGNLGQDPE VRYMPSGGAV ANITIATSET WRDKATGEQK EKTEWHRVTL
     YGKLAEVAGE YLRKGSQVYI EGQLQTRKWQ DQSGQDRYST EVVVQGYNGI MQMLGGRAQQ
     GGMPAQGGMN VPAQQGSWGQ PQQPAKQHQP MQQSAPQQYS QPQYNEPPMD FDDDIPF