SSDNA_BPT5
ID SSDNA_BPT5 Reviewed; 257 AA.
AC P20376; Q66LT9;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=Probable ssDNA-binding protein;
DE AltName: Full=Protein D11;
GN Name=D11;
GN ORFNames=T5.126 {ECO:0000312|EMBL:AAS77172.1},
GN T5p124 {ECO:0000312|EMBL:AAU05263.1};
OS Escherichia phage T5 (Enterobacteria phage T5).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus.
OX NCBI_TaxID=2695836;
OH NCBI_TaxID=562; Escherichia coli.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION.
RX PubMed=3057441; DOI=10.1093/nar/16.21.10353;
RA Kaliman A.V., Kryukov V.M., Bayev A.A.;
RT "The nucleotide sequence of the region of bacteriophage T5 early genes D10-
RT D15.";
RL Nucleic Acids Res. 16:10353-10354(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Ksenzenko V.N., Kaliman A.V., Krutilina A.I., Shlyapnikov M.G.;
RT "Bacteriophage T5 complete genome.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND INDUCTION.
RC STRAIN=ATCC 11303-B5 {ECO:0000312|EMBL:AAX12054.1};
RX PubMed=15661140; DOI=10.1016/j.virol.2004.10.049;
RA Wang J., Jiang Y., Vincent M., Sun Y., Yu H., Wang J., Bao Q., Kong H.,
RA Hu S.;
RT "Complete genome sequence of bacteriophage T5.";
RL Virology 332:45-65(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=St0 deletion mutant;
RX PubMed=24198424; DOI=10.1128/jvi.02262-13;
RA Zivanovic Y., Confalonieri F., Ponchon L., Lurz R., Chami M., Flayhan A.,
RA Renouard M., Huet A., Decottignies P., Davidson A.R., Breyton C.,
RA Boulanger P.;
RT "Insights into bacteriophage T5 structure from analysis of its
RT morphogenesis genes and protein components.";
RL J. Virol. 88:1162-1174(2014).
RN [5]
RP IDENTIFICATION, AND PROBABLE FUNCTION.
RX PubMed=24029071; DOI=10.1016/j.jmb.2013.09.001;
RA Steigemann B., Schulz A., Werten S.;
RT "Bacteriophage T5 encodes a homolog of the eukaryotic transcription
RT coactivator PC4 implicated in recombination-dependent DNA replication.";
RL J. Mol. Biol. 425:4125-4133(2013).
RN [6]
RP PROBABLE FUNCTION.
RX PubMed=24482743; DOI=10.4161/bact.27304;
RA Werten S.;
RT "Identification of the ssDNA-binding protein of bacteriophage T5:
RT Implications for T5 replication.";
RL Bacteriophage 3:E27304-E27304(2013).
CC -!- FUNCTION: Required during DNA replication. Displaced viral DNA strands
CC are transiently coated with the ssDNA-binding protein. It is then
CC probably removed by the replisome that performs lagging strand
CC synthesis or during the events that lead up to the recombination
CC process. {ECO:0000305|PubMed:24029071, ECO:0000305|PubMed:24482743}.
CC -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC {ECO:0000269|PubMed:3057441, ECO:0000305|PubMed:15661140}.
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DR EMBL; AY543070; AAS77172.1; -; Genomic_DNA.
DR EMBL; AY692264; AAU05263.1; -; Genomic_DNA.
DR EMBL; AY587007; AAX12054.1; -; Genomic_DNA.
DR PIR; S10131; WBBPT5.
DR RefSeq; YP_006954.1; NC_005859.1.
DR GeneID; 2777607; -.
DR KEGG; vg:2777607; -.
DR Proteomes; UP000002107; Genome.
DR Proteomes; UP000002141; Genome.
DR Proteomes; UP000002503; Genome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0039693; P:viral DNA genome replication; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW DNA replication; DNA-binding; Early protein; Reference proteome;
KW Viral DNA replication.
FT CHAIN 1..257
FT /note="Probable ssDNA-binding protein"
FT /id="PRO_0000165215"
FT REGION 222..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 257 AA; 28910 MW; 350E13EEE441C9BF CRC64;
MAKSWGETTG GSNDKIEFLK FNNGITRVRI VSGVLPRYVY WLTNKEGSVA PFECLRFNRD
KESFVRGKAD PVHELGFFEK ELDKDGNRVP LKPKKNYIAF VIDRSDNKLK VMEVKATILK
GIQSIMKQLN LATPFDIDIS IEKKGKGFDT EYDVQQIAAM QFQIKLQDPN SAESKQYAAD
VDLIGEAMCD EDGDIIKFEK VPSLEQTYPV PTYEEQKEAI QAFMEGRENK DDDAKSGNSN
AGSQKGIDQE AASDLDD