SSGB_KINRD
ID SSGB_KINRD Reviewed; 165 AA.
AC A6WCJ4;
DT 20-JAN-2016, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Sporulation-specific cell division protein SsgB {ECO:0000303|PubMed:19567872};
DE AltName: Full=Sporulation of Streptomyces griseus-like protein B {ECO:0000303|PubMed:19567872};
DE AltName: Full=SsgA-like protein B {ECO:0000303|PubMed:19567872};
DE Short=SALP B {ECO:0000303|PubMed:19567872};
GN Name=ssgB {ECO:0000303|PubMed:19567872};
GN OrderedLocusNames=Krad_3069 {ECO:0000312|EMBL:ABS04533.1};
OS Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216).
OC Bacteria; Actinobacteria; Kineosporiales; Kineosporiaceae; Kineococcus.
OX NCBI_TaxID=266940 {ECO:0000312|EMBL:ABS04533.1};
RN [1] {ECO:0000312|Proteomes:UP000001116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-149 / DSM 14245 / SRS30216
RC {ECO:0000312|Proteomes:UP000001116};
RX PubMed=19057647; DOI=10.1371/journal.pone.0003878;
RA Bagwell C.E., Bhat S., Hawkins G.M., Smith B.W., Biswas T., Hoover T.R.,
RA Saunders E., Han C.S., Tsodikov O.V., Shimkets L.J.;
RT "Survival in nuclear waste, extreme resistance, and potential applications
RT gleaned from the genome sequence of Kineococcus radiotolerans SRS30216.";
RL PLoS ONE 3:e3878-e3878(2008).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 3-165, AND FUNCTION.
RC STRAIN=ATCC BAA-149 / DSM 14245 / SRS30216 {ECO:0000303|PubMed:19567872};
RX PubMed=19567872; DOI=10.1074/jbc.m109.018564;
RA Xu Q., Traag B.A., Willemse J., McMullan D., Miller M.D., Elsliger M.A.,
RA Abdubek P., Astakhova T., Axelrod H.L., Bakolitsa C., Carlton D., Chen C.,
RA Chiu H.J., Chruszcz M., Clayton T., Das D., Deller M.C., Duan L.,
RA Ellrott K., Ernst D., Farr C.L., Feuerhelm J., Grant J.C., Grzechnik A.,
RA Grzechnik S.K., Han G.W., Jaroszewski L., Jin K.K., Klock H.E., Knuth M.W.,
RA Kozbial P., Krishna S.S., Kumar A., Marciano D., Minor W., Mommaas A.M.,
RA Morse A.T., Nigoghossian E., Nopakun A., Okach L., Oommachen S.,
RA Paulsen J., Puckett C., Reyes R., Rife C.L., Sefcovic N., Tien H.J.,
RA Trame C.B., van den Bedem H., Wang S., Weekes D., Hodgson K.O., Wooley J.,
RA Deacon A.M., Godzik A., Lesley S.A., Wilson I.A., van Wezel G.P.;
RT "Structural and functional characterizations of SsgB, a conserved activator
RT of developmental cell division in morphologically complex actinomycetes.";
RL J. Biol. Chem. 284:25268-25279(2009).
CC -!- FUNCTION: Involved in sporulation-specific cell division
CC (PubMed:19567872). Required for early stages of sporulation. Important
CC in the process of growth cessation prior to sporulation-specific cell
CC division. Recruits cell division protein FtsZ to the future septum
CC sites and tethers the contractile ring structure (Z ring) to the
CC cytoplasmic membrane during sporulation. Stimulates polymerization and
CC filament length of FtsZ in vitro (By similarity).
CC {ECO:0000250|UniProtKB:Q47N25, ECO:0000250|UniProtKB:Q9L268,
CC ECO:0000269|PubMed:19567872}.
CC -!- SUBUNIT: Interacts with SsgA. Interacts with FtsZ (via N-terminus).
CC {ECO:0000250|UniProtKB:Q47N25, ECO:0000250|UniProtKB:Q9L268}.
CC -!- SUBCELLULAR LOCATION: Cell septum {ECO:0000250|UniProtKB:Q9L268}.
CC Note=Localizes to the divisome in sporogenic aerial hyphae in a ladder-
CC like manner. Temporospatial localization is controlled by SsgA and it
CC colocalizes with SsgA in presporulation foci. Localizes to the septum
CC sites prior to FtsZ and after that colocalizes with FtsZ at the
CC divisome throughout cell division. {ECO:0000250|UniProtKB:Q9L268}.
CC -!- SIMILARITY: Belongs to the SsgA family. {ECO:0000305}.
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DR EMBL; CP000750; ABS04533.1; -; Genomic_DNA.
DR AlphaFoldDB; A6WCJ4; -.
DR SMR; A6WCJ4; -.
DR STRING; 266940.Krad_3069; -.
DR EnsemblBacteria; ABS04533; ABS04533; Krad_3069.
DR KEGG; kra:Krad_3069; -.
DR eggNOG; ENOG5032RFA; Bacteria.
DR HOGENOM; CLU_126599_0_1_11; -.
DR OMA; NDEPVEW; -.
DR Proteomes; UP000001116; Chromosome.
DR GO; GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 2.30.31.20; -; 1.
DR InterPro; IPR006776; SsgB.
DR InterPro; IPR038658; SsgB_sf.
DR Pfam; PF04686; SsgA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome; Septation; Sporulation.
FT CHAIN 1..165
FT /note="Sporulation-specific cell division protein SsgB"
FT /id="PRO_0000435311"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 165 AA; 17971 MW; A05E2B349316D316 CRC64;
MLVGNSWTRS LEPVSGHEHT EVDVPALPHR KTEVDVDVSL RLRTTSGPGL PVPASLHYGA
DDPYAIHAVF RGGDTDVEWV FARDLLREGL SAPAGAGDVQ VQPCSDSPDG RPRVLLRLSS
PDGNAELEAD ESDVRRFLRR ADALVPPGRE TRHLDLDELI ARLVS
