SSGB_SALTO
ID SSGB_SALTO Reviewed; 143 AA.
AC A4X5B6;
DT 20-JAN-2016, integrated into UniProtKB/Swiss-Prot.
DT 29-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Sporulation-specific cell division protein SsgB {ECO:0000303|PubMed:19567872};
DE AltName: Full=Sporulation of Streptomyces griseus-like protein B {ECO:0000303|PubMed:19567872};
DE AltName: Full=SsgA-like protein B {ECO:0000303|PubMed:19567872};
DE Short=SALP B {ECO:0000303|PubMed:19567872};
GN Name=ssgB {ECO:0000303|PubMed:19567872};
GN OrderedLocusNames=Strop_1600 {ECO:0000312|EMBL:ABP54066.1};
OS Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440).
OC Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
OC Salinispora.
OX NCBI_TaxID=369723 {ECO:0000312|EMBL:ABP54066.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC STRAIN=ATCC BAA-916 / DSM 44818 / CNB-440 {ECO:0000303|PubMed:19567872};
RX PubMed=19567872; DOI=10.1074/jbc.m109.018564;
RA Xu Q., Traag B.A., Willemse J., McMullan D., Miller M.D., Elsliger M.A.,
RA Abdubek P., Astakhova T., Axelrod H.L., Bakolitsa C., Carlton D., Chen C.,
RA Chiu H.J., Chruszcz M., Clayton T., Das D., Deller M.C., Duan L.,
RA Ellrott K., Ernst D., Farr C.L., Feuerhelm J., Grant J.C., Grzechnik A.,
RA Grzechnik S.K., Han G.W., Jaroszewski L., Jin K.K., Klock H.E., Knuth M.W.,
RA Kozbial P., Krishna S.S., Kumar A., Marciano D., Minor W., Mommaas A.M.,
RA Morse A.T., Nigoghossian E., Nopakun A., Okach L., Oommachen S.,
RA Paulsen J., Puckett C., Reyes R., Rife C.L., Sefcovic N., Tien H.J.,
RA Trame C.B., van den Bedem H., Wang S., Weekes D., Hodgson K.O., Wooley J.,
RA Deacon A.M., Godzik A., Lesley S.A., Wilson I.A., van Wezel G.P.;
RT "Structural and functional characterizations of SsgB, a conserved activator
RT of developmental cell division in morphologically complex actinomycetes.";
RL J. Biol. Chem. 284:25268-25279(2009).
RN [2] {ECO:0000312|Proteomes:UP000000235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-916 / DSM 44818 / CNB-440
RC {ECO:0000312|Proteomes:UP000000235};
RX PubMed=17563368; DOI=10.1073/pnas.0700962104;
RA Udwary D.W., Zeigler L., Asolkar R.N., Singan V., Lapidus A., Fenical W.,
RA Jensen P.R., Moore B.S.;
RT "Genome sequencing reveals complex secondary metabolome in the marine
RT actinomycete Salinispora tropica.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:10376-10381(2007).
CC -!- FUNCTION: Involved in sporulation-specific cell division
CC (PubMed:19567872). Required for early stages of sporulation. Important
CC in the process of growth cessation prior to sporulation-specific cell
CC division. Recruits cell division protein FtsZ to the future septum
CC sites and tethers the contractile ring structure (Z ring) to the
CC cytoplasmic membrane during sporulation. Stimulates polymerization and
CC filament length of FtsZ in vitro (By similarity).
CC {ECO:0000250|UniProtKB:Q47N25, ECO:0000250|UniProtKB:Q9L268,
CC ECO:0000269|PubMed:19567872}.
CC -!- SUBUNIT: Interacts with SsgA. Interacts with FtsZ (via N-terminus).
CC {ECO:0000250|UniProtKB:Q47N25, ECO:0000250|UniProtKB:Q9L268}.
CC -!- SUBCELLULAR LOCATION: Cell septum {ECO:0000250|UniProtKB:Q9L268}.
CC Note=Localizes to the divisome in sporogenic aerial hyphae in a ladder-
CC like manner. Temporospatial localization is controlled by SsgA and it
CC colocalizes with SsgA in presporulation foci. Localizes to the septum
CC sites prior to FtsZ and after that colocalizes with FtsZ at the
CC divisome throughout cell division. {ECO:0000250|UniProtKB:Q9L268}.
CC -!- SIMILARITY: Belongs to the SsgA family. {ECO:0000305}.
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DR EMBL; CP000667; ABP54066.1; -; Genomic_DNA.
DR RefSeq; WP_011905498.1; NC_009380.1.
DR AlphaFoldDB; A4X5B6; -.
DR SMR; A4X5B6; -.
DR STRING; 369723.Strop_1600; -.
DR EnsemblBacteria; ABP54066; ABP54066; Strop_1600.
DR KEGG; stp:Strop_1600; -.
DR PATRIC; fig|369723.5.peg.1638; -.
DR eggNOG; ENOG5032RFA; Bacteria.
DR HOGENOM; CLU_126599_0_1_11; -.
DR OMA; NDEPVEW; -.
DR Proteomes; UP000000235; Chromosome.
DR GO; GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 2.30.31.20; -; 1.
DR InterPro; IPR006776; SsgB.
DR InterPro; IPR038658; SsgB_sf.
DR Pfam; PF04686; SsgA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome; Septation; Sporulation.
FT CHAIN 1..143
FT /note="Sporulation-specific cell division protein SsgB"
FT /id="PRO_0000435313"
SQ SEQUENCE 143 AA; 15561 MW; 539F0DCA1A34BD13 CRC64;
MSVIRPTTVE VETSLRLVAP DATALPVRAS LRYDPADPYA VHVLFHAESA GGEAVSWSFA
RELLVTGLDE PAGIGDVRVW PWATPRGDFV ALALSSPDGN ALFEVPRSVL VRFLRRTYVV
VARGREAEHL DVDTAVNRLL AGR
