SSL5_ARATH
ID SSL5_ARATH Reviewed; 371 AA.
AC Q9CAZ7; Q9SD06;
DT 11-DEC-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Protein STRICTOSIDINE SYNTHASE-LIKE 5 {ECO:0000303|PubMed:10777701};
DE Short=AtSSL5 {ECO:0000303|PubMed:10777701};
DE AltName: Full=Protein YELLOW-LEAF-SPECIFIC GENE 2 {ECO:0000303|PubMed:11230571};
DE Flags: Precursor;
GN Name=SSL5 {ECO:0000303|PubMed:10777701};
GN Synonyms=YLS2 {ECO:0000303|PubMed:11230571};
GN OrderedLocusNames=At3g51430 {ECO:0000312|Araport:AT3G51430};
GN ORFNames=F26O13.70 {ECO:0000312|EMBL:CAB63007.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND
RP INDUCTION.
RX PubMed=11230571; DOI=10.1093/pcp/pce021;
RA Yoshida S., Ito M., Nishida I., Watanabe A.;
RT "Isolation and RNA gel blot analysis of genes that could serve as potential
RT molecular markers for leaf senescence in Arabidopsis thaliana.";
RL Plant Cell Physiol. 42:170-178(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Carninci P., Hayashizaki Y.,
RA Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA Shinozaki K., Ecker J.R.;
RT "Arabidopsis cDNA clones.";
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=10777701; DOI=10.1006/bbrc.2000.2598;
RA Fabbri M., Delp G., Schmidt O., Theopold U.;
RT "Animal and plant members of a gene family with similarity to alkaloid-
RT synthesizing enzymes.";
RL Biochem. Biophys. Res. Commun. 271:191-196(2000).
RN [8]
RP DEVELOPMENTAL STAGE.
RX PubMed=16603661; DOI=10.1104/pp.106.079293;
RA van der Graaff E., Schwacke R., Schneider A., Desimone M., Fluegge U.-I.,
RA Kunze R.;
RT "Transcription analysis of arabidopsis membrane transporters and hormone
RT pathways during developmental and induced leaf senescence.";
RL Plant Physiol. 141:776-792(2006).
RN [9]
RP INDUCTION, AND GENE FAMILY.
RC STRAIN=cv. Columbia;
RX PubMed=19121120; DOI=10.1111/j.1438-8677.2008.00139.x;
RA Sohani M.M., Schenk P.M., Schultz C.J., Schmidt O.;
RT "Phylogenetic and transcriptional analysis of a strictosidine synthase-like
RT gene family in Arabidopsis thaliana reveals involvement in plant defence
RT responses.";
RL Plant Biol. 11:105-117(2009).
CC -!- SUBCELLULAR LOCATION: Vacuole {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9CAZ7-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in cauline leaves and flowers.
CC {ECO:0000269|PubMed:11230571}.
CC -!- DEVELOPMENTAL STAGE: Up-regulated in leaves during natural senescence.
CC {ECO:0000269|PubMed:11230571, ECO:0000269|PubMed:16603661}.
CC -!- INDUCTION: By salicylic acid (SA), jasmonic acid (MJ), ethylene,
CC abscisic acid (ABA), dark and infection with the fungal pathogen
CC A.brassicicola and cucumber mosaic virus (CMV).
CC {ECO:0000269|PubMed:11230571, ECO:0000269|PubMed:19121120}.
CC -!- SIMILARITY: Belongs to the strictosidine synthase family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB63007.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB047805; BAB32882.1; -; mRNA.
DR EMBL; AL133452; CAB63007.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE78791.1; -; Genomic_DNA.
DR EMBL; AY065039; AAL57676.1; -; mRNA.
DR EMBL; AF462858; AAL58944.1; -; mRNA.
DR EMBL; BT010753; AAR23723.1; -; mRNA.
DR EMBL; AY087326; AAM64876.1; -; mRNA.
DR PIR; T45774; T45774.
DR RefSeq; NP_566951.1; NM_115002.4. [Q9CAZ7-1]
DR AlphaFoldDB; Q9CAZ7; -.
DR SMR; Q9CAZ7; -.
DR STRING; 3702.AT3G51430.1; -.
DR PaxDb; Q9CAZ7; -.
DR PRIDE; Q9CAZ7; -.
DR ProteomicsDB; 228372; -. [Q9CAZ7-1]
DR EnsemblPlants; AT3G51430.1; AT3G51430.1; AT3G51430. [Q9CAZ7-1]
DR GeneID; 824306; -.
DR Gramene; AT3G51430.1; AT3G51430.1; AT3G51430. [Q9CAZ7-1]
DR KEGG; ath:AT3G51430; -.
DR Araport; AT3G51430; -.
DR TAIR; locus:2081845; AT3G51430.
DR eggNOG; KOG1520; Eukaryota.
DR InParanoid; Q9CAZ7; -.
DR OMA; EDWVFTG; -.
DR PhylomeDB; Q9CAZ7; -.
DR BRENDA; 4.3.3.2; 399.
DR PRO; PR:Q9CAZ7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9CAZ7; baseline and differential.
DR Genevisible; Q9CAZ7; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:TAIR.
DR GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0009723; P:response to ethylene; IEP:UniProtKB.
DR GO; GO:0009620; P:response to fungus; IEP:UniProtKB.
DR GO; GO:0009753; P:response to jasmonic acid; IEP:UniProtKB.
DR GO; GO:0009751; P:response to salicylic acid; IEP:UniProtKB.
DR GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR Gene3D; 2.120.10.30; -; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR018119; Strictosidine_synth_cons-reg.
DR Pfam; PF03088; Str_synth; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycoprotein; Phosphoprotein; Reference proteome;
KW Signal; Vacuole.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..371
FT /note="Protein STRICTOSIDINE SYNTHASE-LIKE 5"
FT /id="PRO_0000424702"
FT MOD_RES 303
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:Q9SD07"
FT CARBOHYD 101
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 137
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 371 AA; 41642 MW; AA33CD77BF218763 CRC64;
MPMFYSSRFL FFFTIVPLLV SIALYQLDTF DPAPVPSEAY ASSTTSIPPL ISDKYLTGAE
FIGVGLLDKP EDIAYHQDSN LIYTGCIDGW VKRVSVHDSA NDSVVEDWVN TGGRPLGIAF
GVHGEVIVAD AYKGLLNISG DGKKTELLTD QAEGVKFKLT DVVAVADNGV LYFTDASYKY
TLHQVKFDIL EGKPHGRLMS FDPTTRVTRV LLKDLYFANG VSMSPDQTHL IFCETPMRRC
SKYYINEERV EVFIQGLPGY PDNIRYDGDG HYWIAMVSGA STLWRLSMKY PFLRKITAIA
AKYGVELMFM KNAGVLQVDL DGNPIAYYHD QRLSHITTGI KIGNYLYCGN ILHSYIIRLD
LLKYPAQKKK L
