SSL8_ARATH
ID SSL8_ARATH Reviewed; 376 AA.
AC Q9M1J7; Q94K89; Q9M456;
DT 07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Protein STRICTOSIDINE SYNTHASE-LIKE 8 {ECO:0000303|PubMed:10777701};
DE Short=AtSSL8 {ECO:0000303|PubMed:10777701};
DE AltName: Full=Strictosidine synthase 5 {ECO:0000303|PubMed:19121120};
DE Short=AtSS5 {ECO:0000303|PubMed:19121120};
DE Flags: Precursor;
GN Name=SSL8 {ECO:0000303|PubMed:10777701};
GN Synonyms=SS5 {ECO:0000303|PubMed:19121120};
GN OrderedLocusNames=At3g57010 {ECO:0000312|Araport:AT3G57010};
GN ORFNames=F24I3.90 {ECO:0000312|EMBL:CAB72171.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 25-376.
RA Mahon P.;
RL Thesis (2000), University of Cambridge, United Kingdom.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=10777701; DOI=10.1006/bbrc.2000.2598;
RA Fabbri M., Delp G., Schmidt O., Theopold U.;
RT "Animal and plant members of a gene family with similarity to alkaloid-
RT synthesizing enzymes.";
RL Biochem. Biophys. Res. Commun. 271:191-196(2000).
RN [6]
RP GENE FAMILY.
RC STRAIN=cv. Columbia;
RX PubMed=19121120; DOI=10.1111/j.1438-8677.2008.00139.x;
RA Sohani M.M., Schenk P.M., Schultz C.J., Schmidt O.;
RT "Phylogenetic and transcriptional analysis of a strictosidine synthase-like
RT gene family in Arabidopsis thaliana reveals involvement in plant defence
RT responses.";
RL Plant Biol. 11:105-117(2009).
CC -!- SUBCELLULAR LOCATION: Vacuole {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the strictosidine synthase family.
CC {ECO:0000305}.
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DR EMBL; AL138655; CAB72171.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE79598.1; -; Genomic_DNA.
DR EMBL; AF370181; AAK43996.1; -; mRNA.
DR EMBL; AY142495; AAN13046.1; -; mRNA.
DR EMBL; AJ271473; CAB69786.1; -; mRNA.
DR PIR; T47761; T47761.
DR RefSeq; NP_191260.1; NM_115560.4.
DR AlphaFoldDB; Q9M1J7; -.
DR SMR; Q9M1J7; -.
DR IntAct; Q9M1J7; 1.
DR STRING; 3702.AT3G57010.1; -.
DR PaxDb; Q9M1J7; -.
DR PRIDE; Q9M1J7; -.
DR ProteomicsDB; 245209; -.
DR EnsemblPlants; AT3G57010.1; AT3G57010.1; AT3G57010.
DR GeneID; 824868; -.
DR Gramene; AT3G57010.1; AT3G57010.1; AT3G57010.
DR KEGG; ath:AT3G57010; -.
DR Araport; AT3G57010; -.
DR TAIR; locus:2080660; AT3G57010.
DR eggNOG; KOG1520; Eukaryota.
DR HOGENOM; CLU_023267_2_0_1; -.
DR InParanoid; Q9M1J7; -.
DR OMA; NQERMRL; -.
DR OrthoDB; 757814at2759; -.
DR PhylomeDB; Q9M1J7; -.
DR BioCyc; ARA:AT3G57010-MON; -.
DR PRO; PR:Q9M1J7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M1J7; baseline and differential.
DR Genevisible; Q9M1J7; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:TAIR.
DR GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 2.120.10.30; -; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR018119; Strictosidine_synth_cons-reg.
DR Pfam; PF03088; Str_synth; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Reference proteome; Signal; Vacuole.
FT SIGNAL 1..31
FT /evidence="ECO:0000255"
FT CHAIN 32..376
FT /note="Protein STRICTOSIDINE SYNTHASE-LIKE 8"
FT /evidence="ECO:0000255"
FT /id="PRO_0000431595"
FT CARBOHYD 98
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 172
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 224
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CONFLICT 142
FT /note="A -> G (in Ref. 3; AAK43996)"
FT /evidence="ECO:0000305"
FT CONFLICT 237
FT /note="I -> T (in Ref. 4; CAB69786)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 376 AA; 41980 MW; 87FD39FAFF426543 CRC64;
MPISRRVLTP ITAAPVILAV LCFFFWSSII GPDNLKGTKH VLQDAKTIPL PVDGPESLEF
DPQGEGPYVG VTDGRILKWR GEELGWVDFA YTSPHRDNCS SHEVVPSCGR PLGLSFERKT
GDLYICDGYF GVMKVGPEGG LAELVVDEAE GRKVMFANQG DIDEEEDIFY FNDSSDTYHF
RDVFYVSLSG TKVGRVIRYD MKKKEAKVIM DKLRLPNGLA LSKNGSFVVT CESSTNICHR
IWVKGPKSGT NEVFATLPGS PDNIRRTPTG DFWVALHCKK NLFTRAVLIH TWVGRFFMNT
MKMETVIHFM NGGKPHGIVV KLSGETGEIL EILEDSEGKT VKYVSEAYET KDGKLWIGSV
YWPAVWVLDT SVYDSI
