SSP2_YEAST
ID SSP2_YEAST Reviewed; 371 AA.
AC Q08646; D6W2U4; Q96US5;
DT 01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 147.
DE RecName: Full=Sporulation-specific protein 2;
GN Name=SSP2; OrderedLocusNames=YOR242C; ORFNames=O5251;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBCELLULAR LOCATION, AND
RP VARIANTS SK1 HIS-62 AND GLY-88.
RC STRAIN=SK1;
RX PubMed=12073037; DOI=10.1007/s00438-002-0666-5;
RA Sarkar P.K., Florczyk M.A., McDonough K.A., Nag D.K.;
RT "SSP2, a sporulation-specific gene necessary for outer spore wall assembly
RT in the yeast Saccharomyces cerevisiae.";
RL Mol. Genet. Genomics 267:348-358(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=8972580;
RX DOI=10.1002/(sici)1097-0061(199612)12:15<1575::aid-yea45>3.0.co;2-e;
RA Boyer J., Michaux G., Fairhead C., Gaillon L., Dujon B.;
RT "Sequence and analysis of a 26.9 kb fragment from chromosome XV of the
RT yeast Saccharomyces cerevisiae.";
RL Yeast 12:1575-1586(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- FUNCTION: Essential for sporulation and seems to have a role at the
CC time of, or after, initiation of nuclear division. Appears to have a
CC role in outer spore wall formation. {ECO:0000269|PubMed:12073037}.
CC -!- SUBCELLULAR LOCATION: Spore wall {ECO:0000269|PubMed:12073037}.
CC -!- MISCELLANEOUS: Present with 3000 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; AF418016; AAL13305.1; -; Genomic_DNA.
DR EMBL; Z75150; CAA99463.1; -; Genomic_DNA.
DR EMBL; BK006948; DAA11010.1; -; Genomic_DNA.
DR PIR; S67135; S67135.
DR RefSeq; NP_014885.3; NM_001183661.3.
DR AlphaFoldDB; Q08646; -.
DR BioGRID; 34633; 186.
DR DIP; DIP-4116N; -.
DR MINT; Q08646; -.
DR STRING; 4932.YOR242C; -.
DR PaxDb; Q08646; -.
DR PRIDE; Q08646; -.
DR EnsemblFungi; YOR242C_mRNA; YOR242C; YOR242C.
DR GeneID; 854416; -.
DR KEGG; sce:YOR242C; -.
DR SGD; S000005768; SSP2.
DR VEuPathDB; FungiDB:YOR242C; -.
DR eggNOG; ENOG502RYS8; Eukaryota.
DR HOGENOM; CLU_046455_0_0_1; -.
DR InParanoid; Q08646; -.
DR OMA; FIGFRRF; -.
DR BioCyc; YEAST:G3O-33736-MON; -.
DR PRO; PR:Q08646; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; Q08646; protein.
DR GO; GO:0005619; C:ascospore wall; IDA:SGD.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR GO; GO:0005628; C:prospore membrane; HDA:SGD.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0030437; P:ascospore formation; IMP:SGD.
DR GO; GO:0030476; P:ascospore wall assembly; IMP:SGD.
DR GO; GO:0031954; P:positive regulation of protein autophosphorylation; IDA:SGD.
DR CDD; cd12419; RRM_Ssp2_like; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034250; Ssp2_RRM.
DR SUPFAM; SSF54928; SSF54928; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Sporulation.
FT CHAIN 1..371
FT /note="Sporulation-specific protein 2"
FT /id="PRO_0000072217"
FT VARIANT 62
FT /note="R -> H (in strain: SK1)"
FT /evidence="ECO:0000269|PubMed:12073037"
FT VARIANT 88
FT /note="D -> G (in strain: SK1)"
FT /evidence="ECO:0000269|PubMed:12073037"
SQ SEQUENCE 371 AA; 43100 MW; DA9AACAC7AF1958E CRC64;
MYKNYYSNTE VYKKHKDSGS LRKKALRSRR SSFFSFFNDS SSSNGNEFIG FRRFAKAYLF
GREIGSCGTD SYTPVGANVN KRRLKKEDKN DQQLWKRQHH SQGCFFPIDD DSNKQTEAAV
NKFYENGEYV NQDLIFKGKV YSEESEVVDE KTAGSQNPAL LKTRSISLND IPRGTGISSV
LSQVRGGSLE RIIVYRYDTP ERSLHKVDLF FLNYEGAQSF MRYAKTNIFK VNGVQLKPEW
IFLESTYENI MKEQSVNRII EEEKFISRCL IVKKSSTTAM PNKSNLNKGQ TLENIDIQEL
EKDFQNFGEV LEITPIVSRK LCVSIFFYDI SSAMRAMEEY EQKGSYLYNK YFKTWTIWYG
KDITDQPCID L
