ID   SSPA_ECOL6              Reviewed;         212 AA.
AC   P0ACA4; P05838;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Stringent starvation protein A;
GN   Name=sspA; OrderedLocusNames=c3982;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Forms an equimolar complex with the RNA polymerase holoenzyme
CC       (RNAP) but not with the core enzyme. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GST superfamily. HSP26 family.
CC       {ECO:0000305}.
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DR   EMBL; AE014075; AAN82422.1; -; Genomic_DNA.
DR   RefSeq; WP_000257293.1; NC_004431.1.
DR   AlphaFoldDB; P0ACA4; -.
DR   SMR; P0ACA4; -.
DR   STRING; 199310.c3982; -.
DR   EnsemblBacteria; AAN82422; AAN82422; c3982.
DR   GeneID; 67415939; -.
DR   KEGG; ecc:c3982; -.
DR   eggNOG; COG0625; Bacteria.
DR   HOGENOM; CLU_011226_9_3_6; -.
DR   OMA; ADHYSHR; -.
DR   BioCyc; ECOL199310:C3982-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR   CDD; cd03186; GST_C_SspA; 1.
DR   CDD; cd03059; GST_N_SspA; 1.
DR   InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR040079; Glutathione_S-Trfase.
DR   InterPro; IPR004045; Glutathione_S-Trfase_N.
DR   InterPro; IPR004046; GST_C.
DR   InterPro; IPR034342; SspA_C.
DR   InterPro; IPR034341; SspA_N.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00043; GST_C; 1.
DR   Pfam; PF02798; GST_N; 1.
DR   SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR   SUPFAM; SSF47616; SSF47616; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS50405; GST_CTER; 1.
DR   PROSITE; PS50404; GST_NTER; 1.
PE   3: Inferred from homology;
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..212
FT                   /note="Stringent starvation protein A"
FT                   /id="PRO_0000185878"
FT   DOMAIN          9..87
FT                   /note="GST N-terminal"
FT   DOMAIN          92..209
FT                   /note="GST C-terminal"
SQ   SEQUENCE   212 AA;  24305 MW;  A0FFA98F7131B34F CRC64;
     MAVAANKRSV MTLFSGPTDI YSHQVRIVLA EKGVSFEIEH VEKDNPPQDL IDLNPNQSVP
     TLVDRELTLW ESRIIMEYLD ERFPHPPLMP VYPVARGESR LYMHRIEKDW YTLMNTIING
     SASEADAARK QLREELLAIA PVFGQKPYFL SDEFSLVDCY LAPLLWRLPQ LGIEFSGPGA
     KELKGYMTRV FERDSFLASL TEAEREMRLG RS