ID   SSRB_BOVIN              Reviewed;         183 AA.
AC   Q5E9E4; Q3T162;
DT   10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Translocon-associated protein subunit beta;
DE            Short=TRAP-beta;
DE   AltName: Full=Signal sequence receptor subunit beta;
DE            Short=SSR-beta;
DE   Flags: Precursor;
GN   Name=SSR2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: TRAP proteins are part of a complex whose function is to bind
CC       calcium to the ER membrane and thereby regulate the retention of ER
CC       resident proteins.
CC   -!- SUBUNIT: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-
CC       gamma. Interacts with STING1 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass type I membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAP-beta family. {ECO:0000305}.
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DR   EMBL; BT020976; AAX08993.1; -; mRNA.
DR   EMBL; BC102097; AAI02098.1; -; mRNA.
DR   RefSeq; NP_001015533.1; NM_001015533.1.
DR   AlphaFoldDB; Q5E9E4; -.
DR   STRING; 9913.ENSBTAP00000045096; -.
DR   PaxDb; Q5E9E4; -.
DR   Ensembl; ENSBTAT00000047947; ENSBTAP00000045096; ENSBTAG00000001212.
DR   GeneID; 506530; -.
DR   KEGG; bta:506530; -.
DR   CTD; 6746; -.
DR   VEuPathDB; HostDB:ENSBTAG00000001212; -.
DR   VGNC; VGNC:35320; SSR2.
DR   eggNOG; KOG3317; Eukaryota.
DR   GeneTree; ENSGT00390000005125; -.
DR   InParanoid; Q5E9E4; -.
DR   OMA; ILWHSSK; -.
DR   OrthoDB; 1286165at2759; -.
DR   Proteomes; UP000009136; Chromosome 3.
DR   Bgee; ENSBTAG00000001212; Expressed in prostate gland and 103 other tissues.
DR   ExpressionAtlas; Q5E9E4; baseline and differential.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008856; TRAP_beta.
DR   PIRSF; PIRSF016400; TRAP_beta; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Glycoprotein; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..183
FT                   /note="Translocon-associated protein subunit beta"
FT                   /id="PRO_0000033288"
FT   TOPO_DOM        18..146
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        168..183
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        88
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   183 AA;  20123 MW;  39601BFA7C7D5BEF CRC64;
     MRLLAFAVLA LFAVTQAEEG ARLLASKSLL NRYAVEGRDL TLQYNIYNVG SSAALDVELS
     DDSFPPEDFG IVSGMLNVKW DRIAPASNVS HTVVLRPLKA GYFNFTSATV TYLAQEDGPV
     VIGFTSAPGQ GGILAQREFD RRFSPHFLDW AAFGVMTLPS IGVPLLLWYS SKRKYDTPKT
     KKN