ID   SSRD_BOVIN              Reviewed;         172 AA.
AC   Q2TBX5;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Translocon-associated protein subunit delta;
DE            Short=TRAP-delta;
DE   AltName: Full=Signal sequence receptor subunit delta;
DE            Short=SSR-delta;
DE   Flags: Precursor;
GN   Name=SSR4;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: TRAP proteins are part of a complex whose function is to bind
CC       calcium to the ER membrane and thereby regulate the retention of ER
CC       resident proteins. {ECO:0000250}.
CC   -!- SUBUNIT: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-
CC       gamma. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass type I membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAP-delta family. {ECO:0000305}.
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DR   EMBL; BC109500; AAI09501.1; -; mRNA.
DR   RefSeq; NP_001033592.1; NM_001038503.2.
DR   AlphaFoldDB; Q2TBX5; -.
DR   STRING; 9913.ENSBTAP00000028556; -.
DR   PaxDb; Q2TBX5; -.
DR   PeptideAtlas; Q2TBX5; -.
DR   PRIDE; Q2TBX5; -.
DR   Ensembl; ENSBTAT00000028556; ENSBTAP00000028556; ENSBTAG00000021421.
DR   GeneID; 504438; -.
DR   KEGG; bta:504438; -.
DR   CTD; 6748; -.
DR   VEuPathDB; HostDB:ENSBTAG00000021421; -.
DR   VGNC; VGNC:35322; SSR4.
DR   eggNOG; KOG4088; Eukaryota.
DR   GeneTree; ENSGT00390000008992; -.
DR   HOGENOM; CLU_100264_0_1_1; -.
DR   InParanoid; Q2TBX5; -.
DR   OMA; GPWVNSE; -.
DR   OrthoDB; 1518302at2759; -.
DR   TreeFam; TF313158; -.
DR   Proteomes; UP000009136; Chromosome X.
DR   Bgee; ENSBTAG00000021421; Expressed in caput epididymis and 110 other tissues.
DR   ExpressionAtlas; Q2TBX5; baseline.
DR   GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008855; TRAP-delta.
DR   PANTHER; PTHR12731; PTHR12731; 1.
DR   Pfam; PF05404; TRAP-delta; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Endoplasmic reticulum; Isopeptide bond; Membrane;
KW   Reference proteome; Signal; Transmembrane; Transmembrane helix;
KW   Ubl conjugation.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..172
FT                   /note="Translocon-associated protein subunit delta"
FT                   /id="PRO_0000284957"
FT   TOPO_DOM        25..143
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        165..172
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DISULFID        25..56
FT                   /evidence="ECO:0000250"
FT   CROSSLNK        72
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in ubiquitin)"
FT                   /evidence="ECO:0000250|UniProtKB:P51571"
SQ   SEQUENCE   172 AA;  18814 MW;  11D9240C1AC4CA78 CRC64;
     MAALASLGAL ALLLLSGLSC CSEACVEPQI TPSYYTTSDA VISTETVFIV EISLTCKNRV
     QNMALYADVS GKQFPVTRGQ DVGRYQVSWS LDHKSAHAGT YEVRFFDEES YSLLRKAQRN
     NEDVSVIPPL FTVSVDHRGT WNGPWVSTEV LAAAIGLVIY YLAFSAKSHI QA