ID   SSRD_PONAB              Reviewed;         173 AA.
AC   Q5REH6;
DT   10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 2.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Translocon-associated protein subunit delta;
DE            Short=TRAP-delta;
DE   AltName: Full=Signal sequence receptor subunit delta;
DE            Short=SSR-delta;
DE   Flags: Precursor;
GN   Name=SSR4;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: TRAP proteins are part of a complex whose function is to bind
CC       calcium to the ER membrane and thereby regulate the retention of ER
CC       resident proteins. {ECO:0000250}.
CC   -!- SUBUNIT: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-
CC       gamma. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Single-pass type I membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAP-delta family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAH89831.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CR857553; CAH89831.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001127202.1; NM_001133730.1.
DR   AlphaFoldDB; Q5REH6; -.
DR   STRING; 9601.ENSPPYP00000023341; -.
DR   GeneID; 100174257; -.
DR   KEGG; pon:100174257; -.
DR   CTD; 6748; -.
DR   eggNOG; KOG4088; Eukaryota.
DR   HOGENOM; CLU_100264_0_1_1; -.
DR   InParanoid; Q5REH6; -.
DR   OrthoDB; 1325498at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008855; TRAP-delta.
DR   PANTHER; PTHR12731; PTHR12731; 1.
DR   Pfam; PF05404; TRAP-delta; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Endoplasmic reticulum; Isopeptide bond; Membrane;
KW   Reference proteome; Signal; Transmembrane; Transmembrane helix;
KW   Ubl conjugation.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..173
FT                   /note="Translocon-associated protein subunit delta"
FT                   /id="PRO_0000033294"
FT   TOPO_DOM        24..144
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        166..173
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DISULFID        26..57
FT                   /evidence="ECO:0000250"
FT   CROSSLNK        73
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in ubiquitin)"
FT                   /evidence="ECO:0000250|UniProtKB:P51571"
SQ   SEQUENCE   173 AA;  18999 MW;  063CD2C8F6CE368B CRC64;
     MAAMASLGAL ALLLLSSLSR CSAEACLEPQ ITPSYYTTSD AVISTETVFI VEISLTCKNR
     VQNMALYADV GGKQFPVTRG QDVGRYQVSW SLDHKSAHAG TYEVRFFDEE SYSLLRKAQR
     NNEDISIIPP LFTVSVDHRG TWNGPWVSTE VLAAAIGLVI YYLAFSAKSH IQA