SSRG_BOVIN
ID SSRG_BOVIN Reviewed; 185 AA.
AC Q3SZ87;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Translocon-associated protein subunit gamma;
DE Short=TRAP-gamma;
DE AltName: Full=Signal sequence receptor subunit gamma;
DE Short=SSR-gamma;
GN Name=SSR3;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Heart ventricle;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: TRAP proteins are part of a complex whose function is to bind
CC calcium to the ER membrane and thereby regulate the retention of ER
CC resident proteins. {ECO:0000250}.
CC -!- SUBUNIT: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-
CC gamma. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TRAP-gamma family. {ECO:0000305}.
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DR EMBL; BC103053; AAI03054.1; -; mRNA.
DR RefSeq; NP_001070512.1; NM_001077044.2.
DR AlphaFoldDB; Q3SZ87; -.
DR STRING; 9913.ENSBTAP00000024583; -.
DR PaxDb; Q3SZ87; -.
DR PeptideAtlas; Q3SZ87; -.
DR PRIDE; Q3SZ87; -.
DR Ensembl; ENSBTAT00000024583; ENSBTAP00000024583; ENSBTAG00000018471.
DR GeneID; 767980; -.
DR KEGG; bta:767980; -.
DR CTD; 6747; -.
DR VEuPathDB; HostDB:ENSBTAG00000018471; -.
DR VGNC; VGNC:35321; SSR3.
DR eggNOG; KOG4490; Eukaryota.
DR GeneTree; ENSGT00390000000970; -.
DR HOGENOM; CLU_092935_0_0_1; -.
DR InParanoid; Q3SZ87; -.
DR OMA; TKFTLKH; -.
DR OrthoDB; 1450535at2759; -.
DR TreeFam; TF314998; -.
DR Proteomes; UP000009136; Chromosome 1.
DR Bgee; ENSBTAG00000018471; Expressed in myometrium and 109 other tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR InterPro; IPR009779; SSR3.
DR PANTHER; PTHR13399; PTHR13399; 1.
DR Pfam; PF07074; TRAP-gamma; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Endoplasmic reticulum; Membrane; Phosphoprotein;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..185
FT /note="Translocon-associated protein subunit gamma"
FT /id="PRO_0000284958"
FT TOPO_DOM 1..27
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 49..54
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 77..135
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 136..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 158..163
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOD_RES 1
FT /note="N-acetylmethionine"
FT /evidence="ECO:0000250|UniProtKB:Q9UNL2"
FT MOD_RES 11
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9UNL2"
FT MOD_RES 105
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9DCF9"
SQ SEQUENCE 185 AA; 21075 MW; D8E3A40FEF18A3DA CRC64;
MAPKGGPKQQ SEEDLLLQDF SRNLSAKSSA LFFGNAFIVS AIPIWLYWRI WHMDLIQSAV
LYSVMTLVST YLVAFAYKNV KFVLKHKVAQ KREDAVSKEV TRKLSEADNR KMSRKEKDER
ILWKKNEVAD YEATTFSIFY NNTLFLVLVI VASFFILKNF NPTVNYILSI SASSGLIALL
STGSK
