ID   SSRG_DICDI              Reviewed;         170 AA.
AC   Q55GT5;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Translocon-associated protein subunit gamma;
DE            Short=TRAP-gamma;
DE   AltName: Full=Signal sequence receptor subunit gamma;
DE            Short=SSR-gamma;
GN   Name=ssr3; ORFNames=DDB_G0267524;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: TRAP proteins are part of a complex whose function is to bind
CC       calcium to the ER membrane and thereby regulate the retention of ER
CC       resident proteins. {ECO:0000250}.
CC   -!- SUBUNIT: Heterotrimer of TRAP-alpha, TRAP-beta and TRAP-gamma.
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAP-gamma family. {ECO:0000305}.
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DR   EMBL; AAFI02000003; EAL73215.1; -; Genomic_DNA.
DR   RefSeq; XP_647099.1; XM_642007.1.
DR   AlphaFoldDB; Q55GT5; -.
DR   STRING; 44689.DDB0266493; -.
DR   PaxDb; Q55GT5; -.
DR   EnsemblProtists; EAL73215; EAL73215; DDB_G0267524.
DR   GeneID; 8615903; -.
DR   KEGG; ddi:DDB_G0267524; -.
DR   dictyBase; DDB_G0267524; ssr3.
DR   eggNOG; KOG4490; Eukaryota.
DR   HOGENOM; CLU_1573529_0_0_1; -.
DR   InParanoid; Q55GT5; -.
DR   OMA; TKFTLKH; -.
DR   PhylomeDB; Q55GT5; -.
DR   PRO; PR:Q55GT5; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR   InterPro; IPR009779; SSR3.
DR   PANTHER; PTHR13399; PTHR13399; 1.
DR   Pfam; PF07074; TRAP-gamma; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..170
FT                   /note="Translocon-associated protein subunit gamma"
FT                   /id="PRO_0000328443"
FT   TOPO_DOM        1..24
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        46..51
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        73..121
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        142..145
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   170 AA;  19131 MW;  94CF1725CCDF71A4 CRC64;
     MAEVDEFSAF RHENDVSIEQ RIVYFINSLI VALVPVYLYH AIFFMSIDDH MIIYGSVTLF
     AAIVLTFAYN NIYRMKRLKL SASREHISIA SKNKVGDKKK FAAAQKEVQA LVTSHEAIAA
     SIMYNNAVFL ICVSIFSFII FKNVPLVYNY IISISLGAGL TSFLSTSSKH