ID   SSS2_SCYCA              Reviewed;          80 AA.
AC   P11020;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Spermatid-specific protein S2;
DE   AltName: Full=Basic nuclear protein S2;
OS   Scyliorhinus canicula (Small-spotted catshark) (Squalus canicula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC   Scyliorhinus.
OX   NCBI_TaxID=7830;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=2924768; DOI=10.1111/j.1432-1033.1989.tb14652.x;
RA   Chauviere M., Martinage A., Briand G., Sautiere P., Chevaillier P.;
RT   "Nuclear basic protein transition during sperm differentiation. Primary
RT   structure of the spermatid-specific protein S2 from the dog-fish
RT   Scylliorhinus caniculus.";
RL   Eur. J. Biochem. 180:329-335(1989).
CC   -!- FUNCTION: Involved in nuclear basic protein transition: histones are
CC       replaced by spermatid specific proteins which are themselves replaced
CC       by protamines in late spermatids.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- MISCELLANEOUS: N-terminal half is highly basic, while C-terminal part
CC       is acid.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; S03560; S03560.
DR   AlphaFoldDB; P11020; -.
DR   SMR; P11020; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Chromosome; Developmental protein; Differentiation;
KW   Direct protein sequencing; DNA-binding; Nucleosome core; Nucleus;
KW   Spermatogenesis.
FT   CHAIN           1..80
FT                   /note="Spermatid-specific protein S2"
FT                   /id="PRO_0000106633"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..43
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   80 AA;  9733 MW;  593E18EF33452409 CRC64;
     VKSRYHQRQY RARKRYAKAR RTKKPKRRPK PPRKLRYAPS KKQPKIMKLK LDNEVDNTLK
     AKNKSLNEAL KNRLSLRKHV