SSTY1_MOUSE
ID SSTY1_MOUSE Reviewed; 232 AA.
AC P13675;
DT 01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1990, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Y-linked testis-specific protein 1;
GN Name=Ssty1; Synonyms=Smy;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Testis;
RX PubMed=3562242; DOI=10.1093/nar/15.7.2959;
RA Bishop C.E., Hatat D.;
RT "Molecular cloning and sequence analysis of a mouse Y chromosome RNA
RT transcript expressed in the testis.";
RL Nucleic Acids Res. 15:2959-2969(1987).
RN [2]
RP TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=14667817; DOI=10.1016/s0888-7543(03)00216-7;
RA Toure A., Grigoriev V., Mahadevaiah S.K., Rattigan A., Ojarikre O.A.,
RA Burgoyne P.S.;
RT "A protein encoded by a member of the multicopy Ssty gene family located on
RT the long arm of the mouse Y chromosome is expressed during sperm
RT development.";
RL Genomics 83:140-147(2004).
CC -!- TISSUE SPECIFICITY: Expressed in testis (at protein level).
CC {ECO:0000269|PubMed:14667817}.
CC -!- DEVELOPMENTAL STAGE: Not detectable at 20 days postpartum (dpp), barely
CC detectable at 22 days postpartum and is strongly detected thereafter
CC (at protein level). Expression is restricted to spermatid stages.
CC {ECO:0000269|PubMed:14667817}.
CC -!- SIMILARITY: Belongs to the SPIN/STSY family. {ECO:0000305}.
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DR EMBL; X05260; CAA28881.1; -; mRNA.
DR CCDS; CCDS85867.1; -.
DR PIR; A27503; A27503.
DR RefSeq; NP_033246.2; NM_009220.2.
DR AlphaFoldDB; P13675; -.
DR SMR; P13675; -.
DR STRING; 10090.ENSMUSP00000136379; -.
DR iPTMnet; P13675; -.
DR PhosphoSitePlus; P13675; -.
DR PaxDb; P13675; -.
DR PRIDE; P13675; -.
DR GeneID; 20611; -.
DR KEGG; mmu:20611; -.
DR CTD; 20611; -.
DR MGI; MGI:1314663; Ssty1.
DR eggNOG; ENOG502QRYD; Eukaryota.
DR OrthoDB; 1186172at2759; -.
DR PhylomeDB; P13675; -.
DR BioGRID-ORCS; 20611; 6 hits in 27 CRISPR screens.
DR ChiTaRS; Ssty1; mouse.
DR PRO; PR:P13675; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P13675; protein.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR GO; GO:0035064; F:methylated histone binding; IBA:GO_Central.
DR GO; GO:0007276; P:gamete generation; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 2.80.10.70; -; 1.
DR InterPro; IPR003671; SPIN/Ssty.
DR InterPro; IPR042567; SPIN/Ssty_sf.
DR PANTHER; PTHR10405; PTHR10405; 1.
DR Pfam; PF02513; Spin-Ssty; 3.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..232
FT /note="Y-linked testis-specific protein 1"
FT /id="PRO_0000181372"
SQ SEQUENCE 232 AA; 26796 MW; 52E898D5125548D6 CRC64;
MSSLMKKRRR KSSSNTLRNI VSCRISHSWK EGNEPVTQWK AIVLDQLPTN PSLYFVKYDG
IDSIYVLELY SDDRILNLKV LPPIVVFPQV RDAHLARALV GRAVQHKFER KDGSEVNWRG
VVLAQVPIMK DLFYITYKKD PALYAYQLLD DYKEGNLHMI PDTPPAEERS GDDSDVLIGN
WVEYTRKDGS KKFGKVVYQV LANPSVYFIK FHGDIHIYVY TMVPKILEVE KS