ID   SSU72_CHICK             Reviewed;         194 AA.
AC   Q5ZJQ7;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=RNA polymerase II subunit A C-terminal domain phosphatase SSU72;
DE            Short=CTD phosphatase SSU72;
DE            EC=3.1.3.16;
GN   Name=SSU72; ORFNames=RCJMB04_16f24;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May be involved in the C-terminal domain of RNA polymerase II
CC       dephosphorylation, RNA processing and termination. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:83421; EC=3.1.3.16;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC         COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:61977; EC=3.1.3.16;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Predominantly in the cytosol. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SSU72 phosphatase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ720377; CAG32036.1; -; mRNA.
DR   RefSeq; NP_001007876.1; NM_001007875.1.
DR   AlphaFoldDB; Q5ZJQ7; -.
DR   SMR; Q5ZJQ7; -.
DR   STRING; 9031.ENSGALP00000002256; -.
DR   PaxDb; Q5ZJQ7; -.
DR   Ensembl; ENSGALT00000002258; ENSGALP00000002256; ENSGALG00000001489.
DR   GeneID; 419410; -.
DR   KEGG; gga:419410; -.
DR   CTD; 29101; -.
DR   VEuPathDB; HostDB:geneid_419410; -.
DR   eggNOG; KOG2424; Eukaryota.
DR   GeneTree; ENSGT00390000010165; -.
DR   HOGENOM; CLU_062463_2_1_1; -.
DR   InParanoid; Q5ZJQ7; -.
DR   OMA; PNCYEFG; -.
DR   OrthoDB; 1304061at2759; -.
DR   PhylomeDB; Q5ZJQ7; -.
DR   TreeFam; TF300194; -.
DR   Reactome; R-GGA-6807505; RNA polymerase II transcribes snRNA genes.
DR   PRO; PR:Q5ZJQ7; -.
DR   Proteomes; UP000000539; Chromosome 21.
DR   Bgee; ENSGALG00000001489; Expressed in liver and 14 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IBA:GO_Central.
DR   GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008420; F:RNA polymerase II CTD heptapeptide repeat phosphatase activity; IBA:GO_Central.
DR   GO; GO:0070940; P:dephosphorylation of RNA polymerase II C-terminal domain; IBA:GO_Central.
DR   GO; GO:0006378; P:mRNA polyadenylation; IBA:GO_Central.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; IBA:GO_Central.
DR   InterPro; IPR006811; RNA_pol_II_suA.
DR   PANTHER; PTHR20383; PTHR20383; 1.
DR   Pfam; PF04722; Ssu72; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Hydrolase; mRNA processing; Nucleus;
KW   Protein phosphatase; Reference proteome.
FT   CHAIN           1..194
FT                   /note="RNA polymerase II subunit A C-terminal domain
FT                   phosphatase SSU72"
FT                   /id="PRO_0000330015"
FT   COILED          160..186
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   194 AA;  22574 MW;  31C535EDA686306C CRC64;
     MPSSPLRVAV VCSSNQNRSM EAHNILSKRG FSVRSFGTGT HVKLPGPAPD KPNVYDFKTT
     YDQMYNDLLR KDKELYTQNG ILHMLDRNKR IKPRPERFQN CKDVFDLILT CEERVYDQVV
     EDLNSREQET CQPVHVINVD IQDNHEEATL GAFLICELCQ CIQHTEDMEN EIDELLQEFE
     EKSGRTFLHT VCFY