SSUA_ECOLI
ID SSUA_ECOLI Reviewed; 319 AA.
AC P75853; Q9R7Q5;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-1998, sequence version 2.
DT 03-AUG-2022, entry version 145.
DE RecName: Full=Putative aliphatic sulfonates-binding protein;
DE Flags: Precursor;
GN Name=ssuA; Synonyms=ycbO; OrderedLocusNames=b0936, JW0919;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=10506196; DOI=10.1074/jbc.274.41.29358;
RA Van der Ploeg J.R., Iwanicka-Nowicka R., Bykowski T., Hryniewicz M.M.,
RA Leisinger T.;
RT "The Escherichia coli ssuEADCB gene cluster is required for the utilization
RT of sulfur from aliphatic sulfonates and is regulated by the transcriptional
RT activator Cbl.";
RL J. Biol. Chem. 274:29358-29365(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Part of a binding-protein-dependent transport system for
CC aliphatic sulfonates. Putative binding protein.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein SsuA/TauA
CC family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ237695; CAB40390.1; -; Genomic_DNA.
DR EMBL; U00096; AAC74022.2; -; Genomic_DNA.
DR EMBL; AP009048; BAA35691.2; -; Genomic_DNA.
DR PIR; G64833; G64833.
DR RefSeq; NP_415456.4; NC_000913.3.
DR RefSeq; WP_001244308.1; NZ_SSZK01000002.1.
DR PDB; 2X26; X-ray; 1.75 A; A/B=25-319.
DR PDBsum; 2X26; -.
DR AlphaFoldDB; P75853; -.
DR SMR; P75853; -.
DR BioGRID; 4260023; 11.
DR ComplexPortal; CPX-4313; Aliphatic sulfonate ABC transporter complex.
DR IntAct; P75853; 1.
DR STRING; 511145.b0936; -.
DR TCDB; 3.A.1.17.10; the atp-binding cassette (abc) superfamily.
DR PaxDb; P75853; -.
DR PRIDE; P75853; -.
DR EnsemblBacteria; AAC74022; AAC74022; b0936.
DR EnsemblBacteria; BAA35691; BAA35691; BAA35691.
DR GeneID; 945560; -.
DR KEGG; ecj:JW0919; -.
DR KEGG; eco:b0936; -.
DR PATRIC; fig|1411691.4.peg.1338; -.
DR EchoBASE; EB3471; -.
DR eggNOG; COG0715; Bacteria.
DR HOGENOM; CLU_028871_2_0_6; -.
DR InParanoid; P75853; -.
DR OMA; KTADFQY; -.
DR PhylomeDB; P75853; -.
DR BioCyc; EcoCyc:G6478-MON; -.
DR BioCyc; MetaCyc:G6478-MON; -.
DR EvolutionaryTrace; P75853; -.
DR PRO; PR:P75853; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0042959; F:alkanesulfonate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0042918; P:alkanesulfonate transport; IBA:GO_Central.
DR GO; GO:0010438; P:cellular response to sulfur starvation; IC:ComplexPortal.
DR GO; GO:0006790; P:sulfur compound metabolic process; IGI:EcoliWiki.
DR InterPro; IPR010067; ABC_SsuA_sub-bd.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR InterPro; IPR015168; SsuA/THI5.
DR Pfam; PF09084; NMT1; 1.
DR SMART; SM00062; PBPb; 1.
DR TIGRFAMs; TIGR01728; SsuA_fam; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Periplasm; Reference proteome; Signal; Transport.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..319
FT /note="Putative aliphatic sulfonates-binding protein"
FT /id="PRO_0000031864"
FT STRAND 27..33
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 38..45
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 48..52
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 56..62
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 66..75
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 79..83
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 86..93
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 98..104
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 108..110
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 111..116
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 124..127
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 130..134
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 139..150
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 155..157
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 158..162
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 165..173
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 176..183
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 186..193
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 194..202
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 210..215
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 216..221
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 223..242
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 244..255
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 259..267
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 279..294
FT /evidence="ECO:0007829|PDB:2X26"
FT STRAND 297..300
FT /evidence="ECO:0007829|PDB:2X26"
FT HELIX 304..307
FT /evidence="ECO:0007829|PDB:2X26"
SQ SEQUENCE 319 AA; 34558 MW; B4CB0711F38D53D0 CRC64;
MRNIIKLALA GLLSVSTFAV AAESSPEALR IGYQKGSIGM VLAKSHQLLE KRYPESKISW
VEFPAGPQML EALNVGSIDL GSTGDIPPIF AQAAGADLVY VGVEPPKPKA EVILVAENSP
IKTVADLKGH KVAFQKGSSS HNLLLRALRQ AGLKFTDIQP TYLTPADARA AFQQGNVDAW
AIWDPYYSAA LLQGGVRVLK DGTDLNQTGS FYLAARPYAE KNGAFIQGVL ATFSEADALT
RSQREQSIAL LAKTMGLPAP VIASYLDHRP PTTIKPVNAE VAALQQQTAD LFYENRLVPK
KVDIRQRIWQ PTQLEGKQL
