ID   SSXA1_MOUSE             Reviewed;         101 AA.
AC   B1AUS7; E9RK38;
DT   05-JUL-2017, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2017, sequence version 2.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Protein SSXA1 {ECO:0000305};
DE   AltName: Full=Synovial sarcoma, X member A1 {ECO:0000312|MGI:MGI:2446782};
GN   Name=Ssxa1 {ECO:0000312|MGI:MGI:2446782};
GN   Synonyms=Ssxa {ECO:0000303|PubMed:21725589};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000312|Proteomes:UP000000589};
RN   [1] {ECO:0000312|EMBL:BAJ83776.1}
RP   NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   STRAIN=BALB/cJ {ECO:0000312|EMBL:BAJ83776.1};
RC   TISSUE=Testis {ECO:0000312|EMBL:BAJ83776.1};
RX   PubMed=21725589; DOI=10.3892/ijmm.2011.740;
RA   Ichinokawa M., Miyamoto M., Tanaka K., Kyogoku N., Kuroda A., Maki T.,
RA   Yamamura Y., Hirano S.;
RT   "Sequence confirmation and characterization of the mouse Ssxa gene: Ssxa
RT   protein is cleaved and the N-terminal cleaved fragment translocates into
RT   the nucleus.";
RL   Int. J. Mol. Med. 28:705-710(2011).
RN   [2] {ECO:0000312|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000312|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
CC   -!- FUNCTION: Could act as a modulator of transcription. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:21725589}.
CC   -!- TISSUE SPECIFICITY: Specifically expressed in testis (at protein
CC       level). Not detected in other tissues tested (at protein level).
CC       {ECO:0000269|PubMed:21725589}.
CC   -!- SIMILARITY: Belongs to the SSX family. {ECO:0000305}.
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DR   EMBL; AB618486; BAJ83776.1; -; mRNA.
DR   EMBL; AL671922; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001192015.1; NM_001205086.1.
DR   AlphaFoldDB; B1AUS7; -.
DR   SMR; B1AUS7; -.
DR   STRING; 10090.ENSMUSP00000072395; -.
DR   PaxDb; B1AUS7; -.
DR   PRIDE; B1AUS7; -.
DR   DNASU; 385338; -.
DR   GeneID; 385338; -.
DR   KEGG; mmu:385338; -.
DR   UCSC; uc009sun.1; mouse.
DR   CTD; 385338; -.
DR   MGI; MGI:2446782; Ssxa1.
DR   eggNOG; ENOG502RU1A; Eukaryota.
DR   HOGENOM; CLU_168653_1_0_1; -.
DR   InParanoid; B1AUS7; -.
DR   OrthoDB; 1270676at2759; -.
DR   PhylomeDB; B1AUS7; -.
DR   BioGRID-ORCS; 385338; 0 hits in 34 CRISPR screens.
DR   PRO; PR:B1AUS7; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; B1AUS7; protein.
DR   GO; GO:0005634; C:nucleus; ISO:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR003655; aKRAB.
DR   InterPro; IPR001909; KRAB.
DR   InterPro; IPR036051; KRAB_dom_sf.
DR   InterPro; IPR028804; SSX.
DR   PANTHER; PTHR14112; PTHR14112; 1.
DR   Pfam; PF01352; KRAB; 1.
DR   SMART; SM00349; KRAB; 1.
DR   SUPFAM; SSF109640; SSF109640; 1.
DR   PROSITE; PS50806; KRAB_RELATED; 1.
PE   1: Evidence at protein level;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..101
FT                   /note="Protein SSXA1"
FT                   /id="PRO_0000440991"
FT   DOMAIN          19..83
FT                   /note="KRAB-related"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00120"
FT   REGION          73..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   101 AA;  11929 MW;  6217CE2B7F270478 CRC64;
     MKRRSHSVNL GKTKHKPEET CQAFEDISKY FSKEEWKKLS RSEKITYVYM KRNYTTMTNL
     GLRAHLPDFM ESKERVTKSV LSDSDEVSSH ESQDKRKNPV V