ID   ABHGB_MOUSE             Reviewed;         474 AA.
AC   Q80YU0;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Protein ABHD16B {ECO:0000305};
DE            EC=3.-.-.-;
DE   AltName: Full=Alpha/beta hydrolase domain-containing protein 16B {ECO:0000305};
DE            Short=Abhydrolase domain-containing protein 16B {ECO:0000312|MGI:MGI:3607711};
GN   Name=Abhd16b {ECO:0000312|MGI:MGI:3607711};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. ABHD16 family.
CC       {ECO:0000305}.
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DR   EMBL; BC050777; AAH50777.1; -; mRNA.
DR   CCDS; CCDS17213.1; -.
DR   RefSeq; NP_899004.1; NM_183181.2.
DR   AlphaFoldDB; Q80YU0; -.
DR   SMR; Q80YU0; -.
DR   STRING; 10090.ENSMUSP00000066520; -.
DR   ESTHER; mouse-Abhd16b; ABHD16.
DR   MEROPS; S09.976; -.
DR   PhosphoSitePlus; Q80YU0; -.
DR   MaxQB; Q80YU0; -.
DR   PaxDb; Q80YU0; -.
DR   PeptideAtlas; Q80YU0; -.
DR   PRIDE; Q80YU0; -.
DR   ProteomicsDB; 285628; -.
DR   Antibodypedia; 70808; 8 antibodies from 6 providers.
DR   DNASU; 241850; -.
DR   Ensembl; ENSMUST00000069649; ENSMUSP00000066520; ENSMUSG00000055882.
DR   GeneID; 241850; -.
DR   KEGG; mmu:241850; -.
DR   UCSC; uc008omj.2; mouse.
DR   CTD; 140701; -.
DR   MGI; MGI:3607711; Abhd16b.
DR   VEuPathDB; HostDB:ENSMUSG00000055882; -.
DR   eggNOG; KOG1553; Eukaryota.
DR   GeneTree; ENSGT00940000162803; -.
DR   HOGENOM; CLU_040705_2_0_1; -.
DR   InParanoid; Q80YU0; -.
DR   OMA; FMDRRQH; -.
DR   OrthoDB; 580247at2759; -.
DR   PhylomeDB; Q80YU0; -.
DR   TreeFam; TF314267; -.
DR   BioGRID-ORCS; 241850; 2 hits in 72 CRISPR screens.
DR   PRO; PR:Q80YU0; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; Q80YU0; protein.
DR   Bgee; ENSMUSG00000055882; Expressed in testis and 10 other tissues.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR   GO; GO:0047372; F:acylglycerol lipase activity; IBA:GO_Central.
DR   GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IBA:GO_Central.
DR   GO; GO:0004620; F:phospholipase activity; IBA:GO_Central.
DR   GO; GO:0052651; P:monoacylglycerol catabolic process; IBA:GO_Central.
DR   GO; GO:0006660; P:phosphatidylserine catabolic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..474
FT                   /note="Protein ABHD16B"
FT                   /id="PRO_0000079464"
FT   DOMAIN          175..295
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        248
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        323
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        423
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   474 AA;  53297 MW;  193ABB121D8A1BAE CRC64;
     MCVICFVKAL VHVFKIYLTA NYSYNFRSWP VDFRWDDLHA PSTGNSSQRA LTCAAAAAGV
     WLLHDAALGG DTLTRPPRGA RSQVQCLLQQ IRELPSQLAS YALAHSLGRW LVYPGSMFLM
     TRALMPLLQQ GQERLVDRYR GRRAKLVACD GNEIDTMFMD RRQHPGSHGR GLCLVICCEG
     NAGFYEMGCL SAPLEAGYSV LGWNHPGFGG STGAPFPQHD ANAMDVVVKY ALHRLNFPPA
     HVVVYGWSIG GFTATWATMT YPELGALVLD ATFDDLVPLA LKVMPQSWKG LVVRTVREHF
     NLNVAEQLCC YPGPVLLLRR TQDDVVSTSN HIPSMPSCQV EGDVEGNRGN ELLLRLLQHR
     YPSVMAREGR TVVTRWLRAS NLAQETALYA RYRVDDEWCL ATLRSYRERC QKELDDAEAW
     GPHGLSFPWF VGQGLSARRR RQLALFLARR HLKNLEATHC SPLEPEDFQL PWRL